Protein-ligand interactions / / edited by Holger Gohlke

• Pubblicazione: Weinheim, : Wiley-VCH, 2012
• Edizione: 1st ed.
• Descrizione fisica: 1 online resource (361 p.)
• Disciplina: 572.6; 572/.6; 615.19
• Soggetto topico: Proteins; Ligands (Biochemistry); Ligand binding (Biochemistry); Drugs - Structure-activity relationships; Carrier proteins; Ligands; Proteins - pharmacokinetics; Chemistry Techniques, Analytical - methods; Carrier Proteins
• Classificazione: CHE 802f; CHE 820f; CHE 825f; 540; 570; 610; WD 5100
• Altri autori: GohlkeHolger
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: pt. 1. Binding thermodynamics -- pt. 2. Learning from biophysical experiments -- pt. 3. Modeling protein-ligand interactions -- pt. 4. Challenges in molecular recognition.
• Sommario/riassunto: Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development.The first part provides a basic understanding of the factors governing protein-ligand interaction, followed by a comparison of the four key experimental methods (calorimetry, surface plasmon resonance, NMR and X-ray crystallography) used in generating interaction data. The second half of the book is devoted to in-silico methods of modeling and predicting molecular recognition and binding. Here, as elsewhere in the book, emphasis is place
• Titolo autorizzato: Protein-ligand interactions
• ISBN: 3-527-64596-9; 1-280-66289-1; 9786613639820; 3-527-64594-2; 3-527-64597-7
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910141446103321
• Lo trovi qui: Univ. Federico II
• Serie: Methods and principles in medicinal chemistry ; ; v. 53.