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Autore: |
Kutikhin Anton G
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Titolo: |
Genomics of pattern recognition receptors : applications in oncology and cardiovascular diseases / / Anton G. Kutikhin, Arseniy E. Yuzhalin
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Pubblicazione: | New York, : Springer, 2013 |
Edizione: | 1st ed. 2013. |
Descrizione fisica: | 1 online resource (190 p.) |
Disciplina: | 570 |
572696 | |
574.87 | |
599935 | |
Soggetto topico: | Cell receptors |
Genetics | |
Receptors | |
Immunology | |
Cancer - Research | |
Human genetics | |
Altri autori: |
YuzhalinArseniy E
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Note generali: | Description based upon print version of record. |
Nota di bibliografia: | Includes bibliographical references. |
Nota di contenuto: | The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation -- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword -- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer -- Structural Genomic Variation in Other Toll-like Receptors and Cancer -- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer -- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer -- Structural Genomic Variation in NOD-Like Receptors and Cancer -- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases -- Hot Spots In the Field: Where Should We Go. |
Sommario/riassunto: | This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed. |
Titolo autorizzato: | Genomics of pattern recognition receptors ![]() |
ISBN: | 3-0348-0688-4 |
Formato: | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910437623603321 |
Lo trovi qui: | Univ. Federico II |
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