Genomics of pattern recognition receptors : applications in oncology and cardiovascular diseases / / Anton G. Kutikhin, Arseniy E. Yuzhalin
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| Autore: |
Kutikhin Anton G
|
| Titolo: |
Genomics of pattern recognition receptors : applications in oncology and cardiovascular diseases / / Anton G. Kutikhin, Arseniy E. Yuzhalin
|
| Pubblicazione: | New York, : Springer, 2013 |
| Edizione: | 1st ed. 2013. |
| Descrizione fisica: | 1 online resource (190 p.) |
| Disciplina: | 570 |
| 572696 | |
| 574.87 | |
| 599935 | |
| Soggetto topico: | Cell receptors |
| Genetics | |
| Receptors | |
| Immunology | |
| Cancer - Research | |
| Human genetics | |
| Altri autori: |
YuzhalinArseniy E
|
| Note generali: | Description based upon print version of record. |
| Nota di bibliografia: | Includes bibliographical references. |
| Nota di contenuto: | The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation -- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword -- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer -- Structural Genomic Variation in Other Toll-like Receptors and Cancer -- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer -- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer -- Structural Genomic Variation in NOD-Like Receptors and Cancer -- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases -- Hot Spots In the Field: Where Should We Go. |
| Sommario/riassunto: | This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed. |
| Titolo autorizzato: | Genomics of pattern recognition receptors |
| ISBN: | 3-0348-0688-4 |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910437623603321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |