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[null,"1.","Record Nr.",null,"UNINA9910437623603321"]
[null,null,"Autore",null,"Kutikhin Anton G"]
[null,null,"Titolo",null,"Genomics of Pattern Recognition Receptors : Applications in Oncology and Cardiovascular Diseases / / by Anton G. Kutikhin, Arseniy E. Yuzhalin"]
[null,null,"Pubbl/distr/stampa",null,"Basel : , : Springer Basel : , : Imprint : Springer, , 2013"]
[null,null,"ISBN",null,"3-0348-0688-4"]
[null,null,"Edizione",null,"[1st ed. 2013.]"]
[null,null,"Descrizione fisica",null,"1 online resource (190 p.)"]
[null,null,"Disciplina",null,"570"]
[{"$nulls":4},"572696"]
[{"$nulls":4},"574.87"]
[{"$nulls":4},"599935"]
[null,null,"Soggetti",null,"Proteins "]
[{"$nulls":4},"Immunology"]
[{"$nulls":4},"Cancer research"]
[{"$nulls":4},"Human genetics"]
[{"$nulls":4},"Oncology  "]
[{"$nulls":4},"Cardiology"]
[{"$nulls":4},"Receptors"]
[{"$nulls":4},"Cancer Research"]
[{"$nulls":4},"Human Genetics"]
[{"$nulls":4},"Oncology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[{"$nulls":3},"Livello bibliografico","Monografia"]
[{"$nulls":3},"Note generali","Description based upon print version of record."]
[{"$nulls":3},"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation -- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword -- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer -- Structural Genomic Variation in Other Toll-like Receptors and Cancer -- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer -- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer -- Structural Genomic Variation in NOD-Like Receptors and Cancer -- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases -- Hot Spots In the Field: Where Should We Go."]
[{"$nulls":3},"Sommario/riassunto","This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short "]
[{"$nulls":4},"description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed."]