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Titolo: |
Protein-ligand interactions / / edited by Holger Gohlke
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Pubblicazione: | Weinheim, : Wiley-VCH, 2012 |
Edizione: | 1st ed. |
Descrizione fisica: | 1 online resource (361 p.) |
Disciplina: | 572.6 |
572/.6 | |
615.19 | |
Soggetto topico: | Proteins |
Ligands (Biochemistry) | |
Ligand binding (Biochemistry) | |
Drugs - Structure-activity relationships | |
Carrier proteins | |
Ligands | |
Proteins - pharmacokinetics | |
Chemistry Techniques, Analytical - methods | |
Carrier Proteins | |
Classificazione: | CHE 802f |
CHE 820f | |
CHE 825f | |
540 | |
570 | |
610 | |
WD 5100 | |
Altri autori: |
GohlkeHolger
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Note generali: | Description based upon print version of record. |
Nota di bibliografia: | Includes bibliographical references and index. |
Nota di contenuto: | pt. 1. Binding thermodynamics -- pt. 2. Learning from biophysical experiments -- pt. 3. Modeling protein-ligand interactions -- pt. 4. Challenges in molecular recognition. |
Sommario/riassunto: | Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development.The first part provides a basic understanding of the factors governing protein-ligand interaction, followed by a comparison of the four key experimental methods (calorimetry, surface plasmon resonance, NMR and X-ray crystallography) used in generating interaction data. The second half of the book is devoted to in-silico methods of modeling and predicting molecular recognition and binding. Here, as elsewhere in the book, emphasis is place |
Titolo autorizzato: | Protein-ligand interactions ![]() |
ISBN: | 3-527-64596-9 |
1-280-66289-1 | |
9786613639820 | |
3-527-64594-2 | |
3-527-64597-7 | |
Formato: | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910141446103321 |
Lo trovi qui: | Univ. Federico II |
Opac: | Controlla la disponibilità qui |