Analysis and purification methods in combinatorial chemistry / / edited by Bing Yan
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| Titolo: |
Analysis and purification methods in combinatorial chemistry / / edited by Bing Yan
|
| Pubblicazione: | Hoboken, N.J., : Wiley-Interscience, 2004 |
| Edizione: | 1st ed. |
| Descrizione fisica: | 1 online resource (xiii, 466 pages) : illustrations |
| Disciplina: | 615/.19 |
| Soggetto topico: | Combinatorial chemistry |
| Altri autori: |
YanBing
|
| Note generali: | Description based upon print version of record. |
| Nota di bibliografia: | Includes bibliographical references and index. |
| Nota di contenuto: | Analysis and Purification Methods in Combinatorial Chemistry; CONTENTS; PREFACE; CONTRIBUTORS; PART I ANALYSIS FOR FEASIBILITY AND OPTIMIZATION OF LIBRARY SYNTHESIS; CHAPTER 1 QUANTITATIVE ANALYSIS IN ORGANIC SYNTHESIS WITH NMR SPECTROSCOPY; CHAPTER 2 (19)F GEL-PHASE NMR SPECTROSCOPY FOR REACTION MONITORING AND QUANTIFICATION OF RESIN LOADING; CHAPTER 3 THE APPLICATION OF SINGLE-BEAD FTIR AND COLOR TEST FOR REACTION MONITORING AND BUILDING BLOCK VALIDATION IN COMBINATORIAL LIBRARY SYNTHESIS; CHAPTER 4 HR-MAS NMR ANALYSIS OF COMPOUNDS ATTACHED TO POLYMER SUPPORTS |
| CHAPTER 5 MULTIVARIATE TOOLS FOR REAL-TIME MONITORING AND OPTIMIZATION OF COMBINATORIAL MATERIALS AND PROCESS CONDITIONS; CHAPTER 6 MASS SPECTROMETRY AND SOLUBLE POLYMERIC SUPPORT; PART II HIGH-THROUGHPUT ANALYSIS FOR LIBRARY QUALITY CONTROL; CHAPTER 7 HIGH-THROUGHPUT NMR TECHNIQUES FOR COMBINATORIAL CHEMICAL LIBRARY ANALYSIS; CHAPTER 8 MICELLAR ELECTROKINETIC CHROMATOGRAPHY AS A TOOL FOR COMBINATORIAL CHEMISTRY ANALYSIS: THEORY AND APPLICATIONS; CHAPTER 9 CHARACTERIZATION OF SPLIT-POOL ENCODED COMBINATORIAL LIBRARIES; PART III HIGH-THROUGHPUT PURIFICATION TO IMPROVE LIBRARY QUALITY | |
| CHAPTER 10 STRATEGIES AND METHODS FOR PURIFYING ORGANIC COMPOUNDS AND COMBINATORIAL LIBRARIES; CHAPTER 11 HIGH-THROUGHPUT PURIFICATION: TRIAGE AND OPTIMIZATION; CHAPTER 12 PARALLEL HPLC IN HIGH-THROUGHPUT ANALYSIS AND PURIFICATION; PART IV ANALYSIS FOR COMPOUND STABILITY AND DRUGABILITY; CHAPTER 13 ORGANIC COMPOUND STABILITY IN LARGE, DIVERSE PHARMACEUTICAL SCREENING COLLECTION; CHAPTER 14 QUARTZ CRYSTAL MICROBALANCE IN BIOMOLECULAR RECOGNITION; CHAPTER 15 HIGH-THROUGHPUT PHYSICOCHEMICAL PROFILING: POTENTIAL AND LIMITATIONS; CHAPTER 16 SOLUBILITY IN THE DESIGN OF COMBINATORIAL LIBRARIES; CHAPTER 17 HIGH-THROUGHPUT DETERMINATION OF LOG D VALUES BY LC/MS METHODINDEX | |
| Sommario/riassunto: | Quality measurement, control, and improvement in combinatorial chemistryCombinatorial chemistry has developed rapidly in the past decade, with great advances made by scientists working on analysis and purification of a large number of compounds and the analysis of polymer-bound compounds. However, formidable challenges lie ahead of today's researcher. For example, high-throughput analysis and purification technologies must be further developed to ensure combinatorial libraries are ""purifiable,"" and ""drugable.""To this end, Analysis and Purification Methods in Combinatorial Chemistry |
| Titolo autorizzato: | Analysis and purification methods in combinatorial chemistry |
| ISBN: | 9780471531995 |
| 9786610367856 | |
| 9781280367854 | |
| 1280367857 | |
| 9780470342930 | |
| 0470342935 | |
| 9780471531999 | |
| 0471531995 | |
| 9780471531975 | |
| 0471531979 | |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910821997503321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Chemical analysis ; ; v. 163.