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[null,"1.","Record Nr.",null,"UNINA9910821997503321"]
[null,null,"Titolo",null,"Analysis and purification methods in combinatorial chemistry / / edited by  Bing Yan"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, N.J., : Wiley-Interscience, 2004"]
[null,null,"ISBN",null,"9780471531995"]
[{"$nulls":4},"9786610367856"]
[{"$nulls":4},"9781280367854"]
[{"$nulls":4},"1280367857"]
[{"$nulls":4},"9780470342930"]
[{"$nulls":4},"0470342935"]
[{"$nulls":4},"9780471531999"]
[{"$nulls":4},"0471531995"]
[{"$nulls":4},"9780471531975"]
[{"$nulls":4},"0471531979"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (xiii, 466 pages) : illustrations"]
[null,null,"Collana",null,"Chemical analysis ; ; v. 163"]
[null,null,"Disciplina",null,"615/.19"]
[null,null,"Soggetti",null,"Combinatorial chemistry"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Analysis and Purification Methods in Combinatorial Chemistry; CONTENTS; PREFACE; CONTRIBUTORS; PART I ANALYSIS FOR FEASIBILITY AND OPTIMIZATION OF LIBRARY SYNTHESIS; CHAPTER 1 QUANTITATIVE ANALYSIS IN ORGANIC SYNTHESIS WITH NMR SPECTROSCOPY; CHAPTER 2 (19)F GEL-PHASE NMR SPECTROSCOPY FOR REACTION MONITORING AND QUANTIFICATION OF RESIN LOADING; CHAPTER 3 THE APPLICATION OF SINGLE-BEAD FTIR AND COLOR TEST FOR REACTION MONITORING AND BUILDING BLOCK VALIDATION IN COMBINATORIAL LIBRARY SYNTHESIS; CHAPTER 4 HR-MAS NMR ANALYSIS OF COMPOUNDS ATTACHED TO POLYMER SUPPORTS"]
[{"$nulls":4},"CHAPTER 5 MULTIVARIATE TOOLS FOR REAL-TIME MONITORING AND OPTIMIZATION OF COMBINATORIAL MATERIALS AND PROCESS CONDITIONS; CHAPTER 6 MASS SPECTROMETRY AND SOLUBLE POLYMERIC SUPPORT; PART II HIGH-THROUGHPUT ANALYSIS FOR LIBRARY QUALITY CONTROL; CHAPTER 7 HIGH-THROUGHPUT NMR TECHNIQUES FOR COMBINATORIAL CHEMICAL LIBRARY ANALYSIS; "]
[{"$nulls":4},"CHAPTER 8 MICELLAR ELECTROKINETIC CHROMATOGRAPHY AS A TOOL FOR COMBINATORIAL CHEMISTRY ANALYSIS: THEORY AND APPLICATIONS; CHAPTER 9 CHARACTERIZATION OF SPLIT-POOL ENCODED COMBINATORIAL LIBRARIES; PART III HIGH-THROUGHPUT PURIFICATION TO IMPROVE LIBRARY QUALITY"]
[{"$nulls":4},"CHAPTER 10 STRATEGIES AND METHODS FOR PURIFYING ORGANIC COMPOUNDS AND COMBINATORIAL LIBRARIES; CHAPTER 11 HIGH-THROUGHPUT PURIFICATION: TRIAGE AND OPTIMIZATION; CHAPTER 12 PARALLEL HPLC IN HIGH-THROUGHPUT ANALYSIS AND PURIFICATION; PART IV ANALYSIS FOR COMPOUND STABILITY AND DRUGABILITY; CHAPTER 13 ORGANIC COMPOUND STABILITY IN LARGE, DIVERSE PHARMACEUTICAL SCREENING COLLECTION; CHAPTER 14 QUARTZ CRYSTAL MICROBALANCE IN BIOMOLECULAR RECOGNITION; CHAPTER 15 HIGH-THROUGHPUT PHYSICOCHEMICAL PROFILING: POTENTIAL AND LIMITATIONS; CHAPTER 16 SOLUBILITY IN THE DESIGN OF COMBINATORIAL LIBRARIES; CHAPTER 17 HIGH-THROUGHPUT DETERMINATION OF LOG D VALUES BY LC/MS METHODINDEX"]
[null,null,null,"Sommario/riassunto","Quality measurement, control, and improvement in combinatorial chemistryCombinatorial chemistry has developed rapidly in the past decade, with great advances made by scientists working on analysis and purification of a large number of compounds and the analysis of polymer-bound compounds. However, formidable challenges lie ahead of today's researcher. For example, high-throughput analysis and purification technologies must be further developed to ensure combinatorial libraries are \"\"purifiable,\"\" and \"\"drugable.\"\"To this end, Analysis and Purification Methods in Combinatorial Chemistry"]