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Smart Nanovesicles for Drug Targeting and Delivery / Carlotta Marianecci, Maria Carafa



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Autore: Marianecci Carlotta Visualizza persona
Titolo: Smart Nanovesicles for Drug Targeting and Delivery / Carlotta Marianecci, Maria Carafa Visualizza cluster
Pubblicazione: Basel, Switzerland : , : MDPI, , 2019
Descrizione fisica: 1 electronic resource (198 p.)
Soggetto non controllato: protein corona
buspirone
drug delivery
Plectranthus ecklonii
antiproliferative activity
pancreatic ductal adenocarcinoma
tetraethyl orthosilicate
cancer therapy
nanoparticles
cationic liposomes
Ibuprofen
SBA-15
gastrointestinal stability
mesoporous silica nanoparticles
Parvifloron D
anti-tumor drugs
liposomes
gingiva mesenchymal stromal cells
soy lecithin liposomes
MCM-41
lipophilic compound
multifunctional liposomes
caryophyllene sesquiterpene
drug loading
lamellarity
hCMEC/D3 cells
gold shell
magnetic/plasmonic nanoparticles
pH-sensitive niosomes
hot flushes
nasal delivery system
andrographolide
brain delivery
pancreatic cancer
Pain
exosomes
NSAIDs
freeze-drying
manganese ferrite
surfactant
cytotoxicity
paclitaxel
ovariectomized rat
PAMPA
uptake and safety
nanovesicular nasal carrier
Stober's synthesis
Analgesia
protocells
nanocochleates
squamous cell carcinoma
Persona (resp. second.): CarafaMaria
Sommario/riassunto: Nanovesicles are highly-promising systems for the delivery and/or targeting of drugs, biomolecules and contrast agents. Despite the fact that initial studies in this area were performed on phospholipid vesicles, there is an ever-increasing interest in the use of other molecules to obtain smart vesicular carriers focusing on strategies for targeted delivery. These systems can be obtained using newly synthesized smart molecules, or by intelligent design of opportune carriers to achieve specific delivery to the site of action. The drug/contrast agent-containing vesicles need to be directed to precise locations within the body to obtain desired magnitude and duration of the therapeutic or diagnostic effect. This spatial control in the delivery might open new avenues to modulate drug activity while avoiding side-effects and to optimize contrast agent properties while avoiding a broad distribution in the organism. However, delivering and targeting active substances into specific tissues and cells is still a challenge in designing novel therapeutic approaches against untreatable disorders, such as tumors and degenerative diseases.
Titolo autorizzato: Smart Nanovesicles for Drug Targeting and Delivery  Visualizza cluster
ISBN: 9783038978954
3038978957
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910346689303321
Lo trovi qui: Univ. Federico II
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