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[null,"1.","Record Nr.",null,"UNISA996390339703316"]
[null,null,"Autore",null,"Wither George <1588-1667.>"]
[null,null,"Titolo",null,"Vox & lacrimæ Anglorum, or, The true English-mens complaints to their representatives in Parliament [[electronic resource] ] : humbly tendred to their serious consideration at there next sitting, February the 6th, 1668"]
[null,null,"Pubbl/distr/stampa",null,"[London, : s.n.], 1668"]
[null,null,"Edizione",null,"[The second edition,]"]
[null,null,"Descrizione fisica",null,"18 p"]
[null,null,"Soggetti",null,"Great Britain History Charles II, 1660-1685 Poetry"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Attributed to Wither by Wing and NUC pre-1956 imprints."]
[{"$nulls":4},"Marginal notes explain historical allusions in the work."]
[{"$nulls":4},"Reproduction of original in the Harvard University Library."]
[null,null,null,"Sommario/riassunto","eebo-0062"]
[null,"2.","Record Nr.",null,"UNINA9910346689303321"]
[null,null,"Autore",null,"Marianecci Carlotta"]
[null,null,"Titolo",null,"Smart Nanovesicles for Drug Targeting and Delivery / Carlotta Marianecci, Maria Carafa"]
[null,null,"Pubbl/distr/stampa",null,"MDPI - Multidisciplinary Digital Publishing Institute, 2019"]
[{"$nulls":4},"Basel, Switzerland : , : MDPI, , 2019"]
[null,null,"ISBN",null,"9783038978954"]
[{"$nulls":4},"3038978957"]
[null,null,"Descrizione fisica",null,"1 electronic resource (198 p.)"]
[null,null,"Soggetti",null,"Medicine and Nursing"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Nanovesicles are highly-promising systems for the delivery and/or targeting of drugs, biomolecules and contrast agents. Despite the fact that initial studies in this area were performed on phospholipid vesicles, there is an ever-increasing interest in the use of other molecules to obtain smart vesicular carriers focusing on strategies for targeted delivery. These systems can be obtained using newly synthesized smart molecules, or by intelligent design of opportune carriers to achieve specific delivery to the site of action.   The drug/contrast agent-containing vesicles need to be directed to precise locations within the body to obtain desired magnitude and duration of the therapeutic or diagnostic effect. This spatial control in the delivery might open new avenues to modulate drug activity while avoiding side-effects and to optimize contrast agent properties while avoiding a broad distribution in the organism. However, delivering and targeting active substances into specific tissues and cells is still a challenge in designing novel therapeutic approaches against untreatable disorders, such as tumors and degenerative diseases."]