Mismatch repair deficient cancers diagnosis, treatment and prevention / / John Burn
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| Autore: |
Burn John, MD, MRCP
|
| Titolo: |
Mismatch repair deficient cancers diagnosis, treatment and prevention / / John Burn
|
| Pubblicazione: | London, : Henry Stewart Talks, 2014 |
| Descrizione fisica: | 1 online resource (1 streaming video file (44 min.) : color, sound) |
| Soggetto topico: | Aspirin |
| Cancer - Genetic aspects | |
| Colon (Anatomy) - Cancer - Genetic aspects | |
| Colon (Anatomy) - Cancer - Treatment | |
| Medical genetics | |
| Molecular genetics | |
| Rectum - Cancer - Genetic aspects | |
| Rectum - Cancer - Treatment | |
| Aspirin - therapeutic use | |
| Biomarkers | |
| Colorectal Neoplasms - diagnosis | |
| Colorectal Neoplasms - genetics | |
| Colorectal Neoplasms - therapy | |
| Colorectal Neoplasms, Hereditary Nonpolyposis | |
| DNA Mismatch Repair | |
| Genetics, Medical | |
| Microsatellite Instability | |
| Microsatellite Repeats | |
| Note generali: | Animated audio-visual presentation with synchronized narration. |
| Title from title frames. | |
| Nota di contenuto: | Contents: Lynch syndrome (underlying single gene defect) -- Microsatellites -- Important genes containing repeat sequences -- MSI testing (5 marker panel) -- Mismatch repair (MMR) -- The genomic pathogenesis of colorectal cancer (CRC) -- EGFR and BRAF mutant inhibition -- BRAF colon cancer project -- Methotrexate & MMR deficient tumours -- Africans & bowel cancer (Dennis Burkitt) -- Cancer prevention program (CaPP) -- NSAIDs and reduced colorectal cancer risk -- Aspirin effect on polyps in FAP and colorectal adenoma -- The prevention paradox -- CaPP2 (Colorectal & Lynch syndrome cancers) -- Meta-analysis of cancer deaths with aspirin treatment -- CRCs in people on aspirin (mostly COX2 negative) -- Individual response to aspirin in cancer prevention -- History of salicylate as an essential nutrient -- CaPP3 study -- Peptides created by slippage in microsatellite coding -- Antibodies as a possible biomarker for Lynch syndrome -- The Micoryx vaccine. |
| Titolo autorizzato: | Mismatch repair deficient cancers diagnosis, treatment and prevention |
| Formato: | Videoregistrazioni  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910596997903321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Henry Stewart talks. . -Biomedical & life sciences collection. . -Molecular genetics of human disease.