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Titolo: | Glucose-sensing Receptor in Pancreatic Beta-cells / / edited by Itaru Kojima |
Pubblicazione: | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2018 |
Edizione: | 1st ed. 2018. |
Descrizione fisica: | 1 online resource (73 pages) |
Disciplina: | 573.377 |
Soggetto topico: | Human physiology |
Endocrinology | |
Human Physiology | |
Endocrinology | |
Persona (resp. second.): | KojimaItaru |
Nota di contenuto: | 1 HISTORY OF THE RESEARCH ON THE GLUCOSE RECEPTOR -- 2 Cell-surface Glucoreceptor Recognizing Anomers of Glucose in Pancreatic b-cells -- 3 KATP CHANNEL-INDEPENDENT PATHWAY and THE GLUCORECEPTOR -- 4 Signaling System Activated by the Glucose-sensing Receptor -- 5 The Role of the Glucose-sensing Receptor in Glucose-induced Insulin Secretion in Pancreatic b-cells. |
Sommario/riassunto: | Since the 1970s, there has been much discussion about the “glucoreceptor” and “substrate site” and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the “glucoreceptor theory.” This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells. The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: “glucoreceptor theory”. Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes. . |
Titolo autorizzato: | Glucose-sensing Receptor in Pancreatic Beta-cells |
ISBN: | 981-13-0002-X |
Formato: | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910298420003321 |
Lo trovi qui: | Univ. Federico II |
Opac: | Controlla la disponibilità qui |