Glucose-sensing Receptor in Pancreatic Beta-cells / / edited by Itaru Kojima

• Pubblicazione: Singapore : , : Springer Singapore : , : Imprint : Springer, , 2018
• Edizione: 1st ed. 2018.
• Descrizione fisica: 1 online resource (73 pages)
• Disciplina: 573.377
• Soggetto topico: Human physiology; Endocrinology; Human Physiology
• Persona (resp. second.): KojimaItaru
• Nota di contenuto: 1 HISTORY OF THE RESEARCH ON THE GLUCOSE RECEPTOR -- 2 Cell-surface Glucoreceptor Recognizing Anomers of Glucose in Pancreatic b-cells -- 3 KATP CHANNEL-INDEPENDENT PATHWAY and THE GLUCORECEPTOR -- 4 Signaling System Activated by the Glucose-sensing Receptor -- 5 The Role of the Glucose-sensing Receptor in Glucose-induced Insulin Secretion in Pancreatic b-cells.
• Sommario/riassunto: Since the 1970s, there has been much discussion about the “glucoreceptor” and “substrate site” and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the “glucoreceptor theory.” This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells. The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: “glucoreceptor theory”. Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes. .
• Titolo autorizzato: Glucose-sensing Receptor in Pancreatic Beta-cells
• ISBN: 981-13-0002-X
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910298420003321
• Lo trovi qui: Univ. Federico II