Drug design [[electronic resource] ] : cutting edge approaches / / edited by Darren R. Flower
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| Titolo: |
Drug design [[electronic resource] ] : cutting edge approaches / / edited by Darren R. Flower
|
| Pubblicazione: | Cambridge, U.K., : Royal Society of Chemistry, c2002 |
| Descrizione fisica: | 1 online resource (204 p.) |
| Disciplina: | 615.19 |
| Soggetto topico: | Drugs - Design |
| Drugs - Design - Mathematical models | |
| Artificial intelligence - Medical applications | |
| Drugs - Research - Methodology | |
| Soggetto genere / forma: | Electronic books. |
| Altri autori: |
FlowerDarren R
|
| Note generali: | "Proceedings of the meeting on Cutting Edge Approaches to Drug Design held on 13 March 2001 at the Scientific Societies Lecture Theatre, London, UK"--T.p. verso. |
| Nota di bibliografia: | Includes bibliographical references and index. |
| Nota di contenuto: | CONTENTS; Molecular Informatics: Sharpening Drug Design's Cutting Edge; High-Throughput X-Ray Crystallography for Drug Discovery; Trawling the Genome for G Protein-coupled Receptors: the Importance of Integrating Bioinformatic Approaches; Virtual Screening of Virtual Libraries - an Efficient Strategy for LeadGeneration; Virtual Techniques for Lead Optimisation; The Impact of Physical Organic Chemistry on the Control of Drug-likeProperties; Mutagenesis and Modelling Highlight the Critical Nature of theTM2-loop-TM3 Region of Biogenic Amine GPCRS; Computational Vaccine Design; Subject Index |
| Sommario/riassunto: | Pharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of the latest informatics techniques, this book looks at modelling and bioinformatic strategies; structural genomics and X-ray crystallography; virtual screening; lead optimisation; ADME profiling and vaccine design. A number of relevant case studies, focussing on techniques that have demonstrated their use, will concentrate on G-protein coupled receptors as potential disease targets.Providing details of state-of-the-art research, Drug Design: Cutting Edge Approac |
| Titolo autorizzato: | Drug design |
| ISBN: | 1-84755-070-3 |
| 1-60119-027-1 | |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910450162003321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Special publication (Royal Society of Chemistry (Great Britain)) ; ; no. 279.