03376nam 2200649 a 450 991045016200332120200520144314.01-84755-070-31-60119-027-1(CKB)1000000000238269(EBL)1185420(SSID)ssj0000071754(PQKBManifestationID)11107178(PQKBTitleCode)TC0000071754(PQKBWorkID)10091565(PQKB)10393614(MiAaPQ)EBC1185420(PPN)198475810(Au-PeEL)EBL1185420(CaPaEBR)ebr10621270(CaONFJC)MIL871773(OCoLC)843641090(EXLCZ)99100000000023826920060105d2002 uy 0engur|n|---|||||txtccrDrug design[electronic resource] cutting edge approaches /edited by Darren R. FlowerCambridge, U.K. Royal Society of Chemistryc20021 online resource (204 p.)Special publication ;no. 279"Proceedings of the meeting on Cutting Edge Approaches to Drug Design held on 13 March 2001 at the Scientific Societies Lecture Theatre, London, UK"--T.p. verso.0-85404-816-2 Includes bibliographical references and index.CONTENTS; Molecular Informatics: Sharpening Drug Design's Cutting Edge; High-Throughput X-Ray Crystallography for Drug Discovery; Trawling the Genome for G Protein-coupled Receptors: the Importance of Integrating Bioinformatic Approaches; Virtual Screening of Virtual Libraries - an Efficient Strategy for LeadGeneration; Virtual Techniques for Lead Optimisation; The Impact of Physical Organic Chemistry on the Control of Drug-likeProperties; Mutagenesis and Modelling Highlight the Critical Nature of theTM2-loop-TM3 Region of Biogenic Amine GPCRS; Computational Vaccine Design; Subject IndexPharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of the latest informatics techniques, this book looks at modelling and bioinformatic strategies; structural genomics and X-ray crystallography; virtual screening; lead optimisation; ADME profiling and vaccine design. A number of relevant case studies, focussing on techniques that have demonstrated their use, will concentrate on G-protein coupled receptors as potential disease targets.Providing details of state-of-the-art research, Drug Design: Cutting Edge ApproacSpecial publication (Royal Society of Chemistry (Great Britain)) ;no. 279.DrugsDesignCongressesDrugsDesignMathematical modelsCongressesArtificial intelligenceMedical applicationsCongressesDrugsResearchMethodologyCongressesElectronic books.DrugsDesignDrugsDesignMathematical modelsArtificial intelligenceMedical applicationsDrugsResearchMethodology615.19Flower Darren R472707MiAaPQMiAaPQMiAaPQBOOK9910450162003321Drug design2248041UNINA01011nam a22002651i 450099100356085970753620040615152143.0040802s1946 fr |||||||||||||||||fre b13092509-39ule_instARCHE-104511ExLBiblioteca InterfacoltàitaA.t.i. Arché s.c.r.l. Pandora Sicilia s.r.l.842.4Tristan L'Hermite, François<1601-1655>385817Le page disgracié /Tristan L'Hermite ; préface de Marcel ArlandParis :Stock,c1946323 p. ;19 cmA la promenade ;7Letteratura drammatica franceseSec. 17.Arland, Marcel.b1309250902-04-1405-08-04991003560859707536LE002 Fondo Giudici H 127312002000323934le002C. 1-E0.00-no 00000.i1372596805-08-04Page disgracié289672UNISALENTOle00205-08-04ma -frefr 31