Microdialysis in drug development / / Markus Muller, editor

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Titolo:	Microdialysis in drug development / / Markus Muller, editor
Pubblicazione:	New York, : Springer, 2013
Edizione:	1st ed. 2013.
Descrizione fisica:	1 online resource (341 p.)
Disciplina:	615/.19
	616.8/04754
Soggetto topico:	Drug development
	Brain microdialysis
Altri autori:	MüllerMarkus <1967 August 23->
Note generali:	Description based upon print version of record.
Nota di bibliografia:	Includes bibliographical references and index.
Nota di contenuto:	pt. 1. General aspects -- pt. 2. Specific topics.
Sommario/riassunto:	In vivo target site concentrations are probably the most important determinant of drug effects. Traditionally, linking drug concentrations to drug effects has been accomplished by modelling blood-derived data, mostly because a direct quantification of tissue concentrations has been beyond technical reach. Today, a direct measurement of target site concentrations is possible by employing microdialysis or complementary approaches such as imaging technologies. Microdialysis, initially conceived in the 1970ies, has become a standard tool in drug development. This comprehensive overview of current microdialysis technology covers general and disease-specific aspects of microdialysis by international experts in the field. It provides useful information for colleagues in academia and industry who are interested PK-PD aspects of drug development.
Titolo autorizzato:	Microdialysis in drug development
ISBN:	1-283-62448-6
	9786613936936
	1-4614-4815-8
Formato:	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione:	Inglese
Record Nr.:	9910437827103321
Lo trovi qui:	Univ. Federico II
Opac:	Controlla la disponibilità qui

Serie: AAPS Advances in the Pharmaceutical Sciences Series, . 2210-7371 ; ; 4

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