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Aptamers in Biotechnology [[electronic resource] /] / edited by Katharina Urmann, Johanna-Gabriela Walter



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Titolo: Aptamers in Biotechnology [[electronic resource] /] / edited by Katharina Urmann, Johanna-Gabriela Walter Visualizza cluster
Pubblicazione: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Edizione: 1st ed. 2020.
Descrizione fisica: 1 online resource (VII, 215 p. 61 illus., 47 illus. in color.)
Disciplina: 572.85
Soggetto topico: Biotechnology
Immunology
Nucleic acids
Nanochemistry
Chromatography
Biomedical engineering
Nucleic Acid Chemistry
Biomedical Engineering and Bioengineering
Persona (resp. second.): UrmannKatharina
WalterJohanna-Gabriela
Nota di contenuto: Biophysical Characterization of Aptamer-Target Interactions -- Impedimetric Aptamer-based Biosensors: Principles and Techniques -- Impedimetric Aptamer-based Biosensors: Applications -- Aptamer-based affinity chromatography for protein extraction and purification -- Aptamers in diagnostic and molecular imaging applications -- Aptamer-modified nanoparticles in medical applications -- Defining Target Product Profiles (TPPs) for Aptamer based diagnostics.
Sommario/riassunto: This book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community. This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology. .
Titolo autorizzato: Aptamers in Biotechnology  Visualizza cluster
ISBN: 3-030-54061-8
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910412150203321
Lo trovi qui: Univ. Federico II
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Serie: Advances in Biochemical Engineering/Biotechnology, . 0724-6145 ; ; 174