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Record Nr. |
UNINA9910412150203321 |
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Titolo |
Aptamers in Biotechnology / / edited by Katharina Urmann, Johanna-Gabriela Walter |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
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ISBN |
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Edizione |
[1st ed. 2020.] |
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Descrizione fisica |
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1 online resource (VII, 215 p. 61 illus., 47 illus. in color.) |
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Collana |
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Advances in Biochemical Engineering/Biotechnology, , 0724-6145 ; ; 174 |
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Disciplina |
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Soggetti |
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Biotechnology |
Immunology |
Nucleic acids |
Nanochemistry |
Chromatography |
Biomedical engineering |
Nucleic Acid Chemistry |
Biomedical Engineering and Bioengineering |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Biophysical Characterization of Aptamer-Target Interactions -- Impedimetric Aptamer-based Biosensors: Principles and Techniques -- Impedimetric Aptamer-based Biosensors: Applications -- Aptamer-based affinity chromatography for protein extraction and purification -- Aptamers in diagnostic and molecular imaging applications -- Aptamer-modified nanoparticles in medical applications -- Defining Target Product Profiles (TPPs) for Aptamer based diagnostics. |
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Sommario/riassunto |
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This book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical |
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discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community. This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology. . |
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