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010   $a3-030-54061-8
024 7 $a10.1007/978-3-030-54061-6
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035   $a(DE-He213)978-3-030-54061-6
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100   $a20200731d2020      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aAptamers in Biotechnology /$fedited by Katharina Urmann, Johanna-Gabriela Walter
205   $a1st ed. 2020.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020.
215   $a1 online resource (VII, 215 p. 61 illus., 47 illus. in color.) 
225 1 $aAdvances in Biochemical Engineering/Biotechnology,$x0724-6145 ;$v174
311   $a3-030-54060-X 
327   $aBiophysical Characterization of Aptamer-Target Interactions -- Impedimetric Aptamer-based Biosensors: Principles and Techniques -- Impedimetric Aptamer-based Biosensors: Applications -- Aptamer-based affinity chromatography for protein extraction and purification -- Aptamers in diagnostic and molecular imaging applications -- Aptamer-modified nanoparticles in medical applications -- Defining Target Product Profiles (TPPs) for Aptamer based diagnostics.
330   $aThis book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community. This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology. .
410  0$aAdvances in Biochemical Engineering/Biotechnology,$x0724-6145 ;$v174
606   $aBiotechnology
606   $aImmunology
606   $aNucleic acids
606   $aNanochemistry
606   $aChromatography
606   $aBiomedical engineering
606   $aBiotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12002
606   $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000
606   $aNucleic Acid Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/L14011
606   $aNanochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C33000
606   $aChromatography$3https://scigraph.springernature.com/ontologies/product-market-codes/C11030
606   $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X
615  0$aBiotechnology.
615  0$aImmunology.
615  0$aNucleic acids.
615  0$aNanochemistry.
615  0$aChromatography.
615  0$aBiomedical engineering.
615 14$aBiotechnology.
615 24$aImmunology.
615 24$aNucleic Acid Chemistry.
615 24$aNanochemistry.
615 24$aChromatography.
615 24$aBiomedical Engineering and Bioengineering.
676   $a572.85
676   $a572.85
702   $aUrmann$b Katharina$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aWalter$b Johanna-Gabriela$4edt$4http://id.loc.gov/vocabulary/relators/edt
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910412150203321
996   $aAptamers in Biotechnology$92547199
997   $aUNINA