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[null,"1.","Record Nr.",null,"UNINA9910412150203321"]
[null,null,"Titolo",null,"Aptamers in Biotechnology / / edited by Katharina Urmann, Johanna-Gabriela Walter"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020"]
[null,null,"ISBN",null,"3-030-54061-8"]
[null,null,"Edizione",null,"[1st ed. 2020.]"]
[null,null,"Descrizione fisica",null,"1 online resource (VII, 215 p. 61 illus., 47 illus. in color.)"]
[null,null,"Collana",null,"Advances in Biochemical Engineering/Biotechnology, , 0724-6145 ; ; 174"]
[null,null,"Disciplina",null,"572.85"]
[null,null,"Soggetti",null,"Biotechnology"]
[{"$nulls":4},"Immunology"]
[{"$nulls":4},"Nucleic acids"]
[{"$nulls":4},"Nanochemistry"]
[{"$nulls":4},"Chromatographic analysis"]
[{"$nulls":4},"Biomedical engineering"]
[{"$nulls":4},"Nucleic Acid Chemistry"]
[{"$nulls":4},"Chromatography"]
[{"$nulls":4},"Biomedical Engineering and Bioengineering"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Biophysical Characterization of Aptamer-Target Interactions -- Impedimetric Aptamer-based Biosensors: Principles and Techniques -- Impedimetric Aptamer-based Biosensors: Applications -- Aptamer-based affinity chromatography for protein extraction and purification -- Aptamers in diagnostic and molecular imaging applications -- Aptamer-modified nanoparticles in medical applications -- Defining Target Product Profiles (TPPs) for Aptamer based diagnostics."]
[null,null,null,"Sommario/riassunto","This book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small "]
[{"$nulls":4},"aptamer-community. This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology. ."]