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Autore: | Valentine Raymond C |
Titolo: | Human Longevity |
Pubblicazione: | CRC Press, 2014 |
Descrizione fisica: | 1 online resource (248 p.) |
Disciplina: | 612.6/7 |
Soggetto topico: | Aging - Genetic aspects |
Mitochondria | |
Oxidative stress | |
Omega-3 fatty acids - Health aspects | |
Classificazione: | MED008000SCI049000TEC012000 |
Altri autori: | ValentineDavid L |
Note generali: | Description based upon print version of record. |
Nota di bibliografia: | Includes bibliographical references at the end of each chapters. |
Nota di contenuto: | Chapter 5: Remarkable Longevity of Queens of Social Insects Likely Involves Dietary Manipulation to Minimize Levels of Polyunsaturates and Decrease Membrane PeroxidationChapter 6: Membrane Peroxidation Hypothesis Helps Explain Longevity in Birds, Rodents, and Whales; Chapter 7: Did Longevity Help Humans Become Super Humans?; Chapter 8: Mitochondrial Diseases and Aging Have Much in Common; Chapter 9: Revised Mitochondrial Hypothesis of Aging Highlights Energy Deficiency Caused by Errors of Replication (Mutations) of mtDNA; Chapter 10: Benefits of Polyunsaturated Mitochondrial Membranes |
Chapter 16: Uncoupling Proteins (UCPs) of Mitochondria Purposely Waste Energy to Prevent Membrane DamageChapter 17: Mitochondrial Fission Protects against Oxidative Stress by Minting a Continuous Supply of Cardiolipin and Other Polyunsaturated Phospholipids; Chapter 18: Mitophagy Eliminates Toxic Mitochondria; Chapter 19: Longevity Genes Likely Protect Membranes; Chapter 20: Aging as a Cardiolipin Disease That Can Be Treated; Back Cover | |
Sommario/riassunto: | More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman's famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging. Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membran |
Titolo autorizzato: | Human Longevity |
ISBN: | 0-429-16877-2 |
1-4665-9487-X | |
Formato: | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910787839903321 |
Lo trovi qui: | Univ. Federico II |
Opac: | Controlla la disponibilità qui |