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Molecular and Cellular Biology of Platelet Formation : Implications in Health and Disease / / edited by Harald Schulze, Joseph Italiano



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Titolo: Molecular and Cellular Biology of Platelet Formation : Implications in Health and Disease / / edited by Harald Schulze, Joseph Italiano Visualizza cluster
Pubblicazione: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Edizione: 1st ed. 2016.
Descrizione fisica: 1 online resource (456 pages)
Disciplina: 612.117
Soggetto topico: Human physiology
Hematology
Cell biology
Gene therapy
Molecular biology
Blood transfusion
Human Physiology
Cell Biology
Gene Therapy
Molecular Medicine
Blood Transfusion Medicine
Persona (resp. second.): SchulzeHarald
ItalianoJoseph
Nota di bibliografia: Includes bibliographical references at the end of each chapters.
Nota di contenuto: I. Thrombopoiesis  1. A short history of the platelet (N.N.) -- 2. Megakaryopoiesis and Platelet biogenesis (Italiano) -- 3. Transcription factors in MKs and platelets (Cantor / Tijssen & Ghavaert) -- 4. Platelet biogenesis in vivo and the Vascular Niche (Schulze). II. Platelet biology.- 5. Platelet contents (Hartwig) -- 6. Platelet signal transduction (Yonis / S. Watson) -- 7. Thrombosis (Bergmeier) -- 8. Platelets and coagulation (N.N.) -- 9. The platelet life span (Kile). III. Animal models   10. Platelets in mice and men (N.N) --   11. Animal models for platelet function (Nieswandt) -- 12. Other animal models /zebrafish (N.N.).     IV. Platelets in Health and Disease.- 13. Platelet parameters and function testing in the clinic (Schulze / Dame) -- 14. Atherothrombosis and Coronary Artery Disease (Nieswandt) -- 15. Thrombocytopenias and Thrombocytopathies (Ballmaier) -- 16. Platelets in myeloproliferative disorders and leukemia (N.N.) -- 17. Platelet Apheresis and Transfusions (N.N) -- 18. Platelet Biogenesis following Stem Cell Transplantation (N.N).
Sommario/riassunto: This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being  written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and research. It represents an indispensable tool for research scientists in biomedicine, vascular biology, hematopoiesis and hemostasis and specifically for scientists in platelet research, as well as for clinicians in the field of hematology and transfusion medicine.  .
Titolo autorizzato: Molecular and Cellular Biology of Platelet Formation  Visualizza cluster
ISBN: 3-319-39562-9
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910163989503321
Lo trovi qui: Univ. Federico II
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