04306nam 22006735 450 991016398950332120200706052311.03-319-39562-910.1007/978-3-319-39562-3(CKB)3710000001051634(MiAaPQ)EBC4801197(DE-He213)978-3-319-39562-3(PPN)19887197X(EXLCZ)99371000000105163420170207d2016 u| 0engurcnu||||||||rdacontentrdamediardacarrierMolecular and Cellular Biology of Platelet Formation Implications in Health and Disease /edited by Harald Schulze, Joseph Italiano1st ed. 2016.Cham :Springer International Publishing :Imprint: Springer,2016.1 online resource (456 pages)3-319-39560-2 Includes bibliographical references at the end of each chapters.I. Thrombopoiesis  1. A short history of the platelet (N.N.) -- 2. Megakaryopoiesis and Platelet biogenesis (Italiano) -- 3. Transcription factors in MKs and platelets (Cantor / Tijssen & Ghavaert) -- 4. Platelet biogenesis in vivo and the Vascular Niche (Schulze). II. Platelet biology.- 5. Platelet contents (Hartwig) -- 6. Platelet signal transduction (Yonis / S. Watson) -- 7. Thrombosis (Bergmeier) -- 8. Platelets and coagulation (N.N.) -- 9. The platelet life span (Kile). III. Animal models   10. Platelets in mice and men (N.N) --   11. Animal models for platelet function (Nieswandt) -- 12. Other animal models /zebrafish (N.N.).     IV. Platelets in Health and Disease.- 13. Platelet parameters and function testing in the clinic (Schulze / Dame) -- 14. Atherothrombosis and Coronary Artery Disease (Nieswandt) -- 15. Thrombocytopenias and Thrombocytopathies (Ballmaier) -- 16. Platelets in myeloproliferative disorders and leukemia (N.N.) -- 17. Platelet Apheresis and Transfusions (N.N) -- 18. Platelet Biogenesis following Stem Cell Transplantation (N.N).This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being  written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and research. It represents an indispensable tool for research scientists in biomedicine, vascular biology, hematopoiesis and hemostasis and specifically for scientists in platelet research, as well as for clinicians in the field of hematology and transfusion medicine.  .Human physiologyHematologyCell biologyGene therapyMolecular biologyBlood transfusionHuman Physiologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B13004Hematologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H3307XCell Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16008Gene Therapyhttps://scigraph.springernature.com/ontologies/product-market-codes/B12020Molecular Medicinehttps://scigraph.springernature.com/ontologies/product-market-codes/B1700XBlood Transfusion Medicinehttps://scigraph.springernature.com/ontologies/product-market-codes/H33029Human physiology.Hematology.Cell biology.Gene therapy.Molecular biology.Blood transfusion.Human Physiology.Hematology.Cell Biology.Gene Therapy.Molecular Medicine.Blood Transfusion Medicine.612.117Schulze Haraldedthttp://id.loc.gov/vocabulary/relators/edtItaliano Josephedthttp://id.loc.gov/vocabulary/relators/edtBOOK9910163989503321Molecular and Cellular Biology of Platelet Formation2527550UNINA