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010   $a3-319-39562-9
024 7 $a10.1007/978-3-319-39562-3
035   $a(CKB)3710000001051634
035   $a(MiAaPQ)EBC4801197
035   $a(DE-He213)978-3-319-39562-3
035   $a(PPN)19887197X
035   $a(EXLCZ)993710000001051634
100   $a20170207d2016      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $2rdacontent
182   $2rdamedia
183   $2rdacarrier
200 10$aMolecular and Cellular Biology of Platelet Formation $eImplications in Health and Disease /$fedited by Harald Schulze, Joseph Italiano
205   $a1st ed. 2016.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016.
215   $a1 online resource (456 pages)
311   $a3-319-39560-2 
320   $aIncludes bibliographical references at the end of each chapters.
327   $aI. Thrombopoiesis  1. A short history of the platelet (N.N.) -- 2. Megakaryopoiesis and Platelet biogenesis (Italiano) -- 3. Transcription factors in MKs and platelets (Cantor / Tijssen & Ghavaert) -- 4. Platelet biogenesis in vivo and the Vascular Niche (Schulze). II. Platelet biology.- 5. Platelet contents (Hartwig) -- 6. Platelet signal transduction (Yonis / S. Watson) -- 7. Thrombosis (Bergmeier) -- 8. Platelets and coagulation (N.N.) -- 9. The platelet life span (Kile). III. Animal models   10. Platelets in mice and men (N.N) --   11. Animal models for platelet function (Nieswandt) -- 12. Other animal models /zebrafish (N.N.).     IV. Platelets in Health and Disease.- 13. Platelet parameters and function testing in the clinic (Schulze / Dame) -- 14. Atherothrombosis and Coronary Artery Disease (Nieswandt) -- 15. Thrombocytopenias and Thrombocytopathies (Ballmaier) -- 16. Platelets in myeloproliferative disorders and leukemia (N.N.) -- 17. Platelet Apheresis and Transfusions (N.N) -- 18. Platelet Biogenesis following Stem Cell Transplantation (N.N).
330   $aThis book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being  written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and research. It represents an indispensable tool for research scientists in biomedicine, vascular biology, hematopoiesis and hemostasis and specifically for scientists in platelet research, as well as for clinicians in the field of hematology and transfusion medicine.  .
606   $aHuman physiology
606   $aHematology
606   $aCell biology
606   $aGene therapy
606   $aMolecular biology
606   $aBlood transfusion
606   $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004
606   $aHematology$3https://scigraph.springernature.com/ontologies/product-market-codes/H3307X
606   $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008
606   $aGene Therapy$3https://scigraph.springernature.com/ontologies/product-market-codes/B12020
606   $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X
606   $aBlood Transfusion Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H33029
615  0$aHuman physiology.
615  0$aHematology.
615  0$aCell biology.
615  0$aGene therapy.
615  0$aMolecular biology.
615  0$aBlood transfusion.
615 14$aHuman Physiology.
615 24$aHematology.
615 24$aCell Biology.
615 24$aGene Therapy.
615 24$aMolecular Medicine.
615 24$aBlood Transfusion Medicine.
676   $a612.117
702   $aSchulze$b Harald$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aItaliano$b Joseph$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910163989503321
996   $aMolecular and Cellular Biology of Platelet Formation$92527550
997   $aUNINA