Antimicrobial Compounds : Current Strategies and New Alternatives / / edited by Tomás G. Villa, Patricia Veiga-Crespo

• Pubblicazione: Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014
• Edizione: 1st ed. 2014.
• Descrizione fisica: 1 online resource (325 p.)
• Disciplina: 616.90461
• Soggetto topico: Microbiology; Medical microbiology; Microbial genetics; Microbial genomics; Pharmaceutical technology; Medical Microbiology; Microbial Genetics and Genomics; Pharmaceutical Sciences/Technology
• Persona (resp. second.): VillaTomás G; Veiga-CrespoPatricia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Strategies for the design and discovery of novel antibiotics using genetic engineering and genome mining -- X-ray and Neutron Scattering Foundations for the Research in Antimicrobials -- Antibacterial, Antiviral and Antifungal Activity of Essential Oils: Mechanisms and Applications -- New antimicrobial agents of plant origin -- Advances in beta-lactam antibiotics -- The Cornerstone of Nucleic Acid-affecting Antibiotics in Bacteria -- Genetic analysis and manipulation of polyene antibiotic gene clusters as a way to produce more effective antifungal compounds -- Enzybiotics: The rush towards prevention and control of multi-resistant bacteria (MRB) -- New cell wall-affecting antifungal antibiotics -- Perspectives in the research on Antimicrobial peptides -- Glycopeptides and bacterial cell walls.
• Sommario/riassunto: Since penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years. This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics.
• Titolo autorizzato: Antimicrobial Compounds
• ISBN: 3-642-40444-8
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910298324903321
• Lo trovi qui: Univ. Federico II