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[null,"1.","Record Nr.",null,"UNINA9910298324903321"]
[null,null,"Titolo",null,"Antimicrobial Compounds : Current Strategies and New Alternatives / / edited by Tomás G. Villa, Patricia Veiga-Crespo"]
[null,null,"Pubbl/distr/stampa",null,"Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014"]
[null,null,"ISBN",null,"3-642-40444-8"]
[null,null,"Edizione",null,"[1st ed. 2014.]"]
[null,null,"Descrizione fisica",null,"1 online resource (325 p.)"]
[null,null,"Disciplina",null,"616.90461"]
[null,null,"Soggetti",null,"Microbiology"]
[{"$nulls":4},"Medical microbiology"]
[{"$nulls":4},"Microbial genetics"]
[{"$nulls":4},"Microbial genomics"]
[{"$nulls":4},"Pharmaceutical technology"]
[{"$nulls":4},"Medical Microbiology"]
[{"$nulls":4},"Microbial Genetics and Genomics"]
[{"$nulls":4},"Pharmaceutical Sciences/Technology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Strategies for the design and discovery of novel antibiotics using genetic engineering and genome mining -- X-ray and Neutron Scattering Foundations for the Research in Antimicrobials -- Antibacterial, Antiviral and Antifungal Activity of Essential Oils: Mechanisms and Applications -- New antimicrobial agents of plant origin -- Advances in beta-lactam antibiotics -- The Cornerstone of Nucleic Acid-affecting Antibiotics in Bacteria -- Genetic analysis and manipulation of polyene antibiotic gene clusters as a way to produce more effective antifungal compounds -- Enzybiotics: The rush towards prevention and control of multi-resistant bacteria (MRB) -- New cell wall-affecting antifungal antibiotics -- Perspectives in the research on Antimicrobial peptides -- Glycopeptides and bacterial cell walls."]
[null,null,null,"Sommario/riassunto","Since penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years. This book reviews the current state-of-the-art in antimicrobial research and "]
[{"$nulls":4},"discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics."]