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010   $a3-642-40444-8
024 7 $a10.1007/978-3-642-40444-3
035   $a(CKB)2550000001152729
035   $a(EBL)1538563
035   $a(SSID)ssj0001048998
035   $a(PQKBManifestationID)11673216
035   $a(PQKBTitleCode)TC0001048998
035   $a(PQKBWorkID)11018818
035   $a(PQKB)11030969
035   $a(MiAaPQ)EBC1538563
035   $a(DE-He213)978-3-642-40444-3
035   $a(PPN)176114726
035   $a(EXLCZ)992550000001152729
100   $a20131018d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aAntimicrobial Compounds $eCurrent Strategies and New Alternatives /$fedited by Tomás G. Villa, Patricia Veiga-Crespo
205   $a1st ed. 2014.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2014.
215   $a1 online resource (325 p.)
300   $aDescription based upon print version of record.
311   $a3-642-40443-X 
320   $aIncludes bibliographical references and index.
327   $aStrategies for the design and discovery of novel antibiotics using genetic engineering and genome mining -- X-ray and Neutron Scattering Foundations for the Research in Antimicrobials -- Antibacterial, Antiviral and Antifungal Activity of Essential Oils: Mechanisms and Applications -- New antimicrobial agents of plant origin -- Advances in beta-lactam antibiotics -- The Cornerstone of Nucleic Acid-affecting Antibiotics in Bacteria -- Genetic analysis and manipulation of polyene antibiotic gene clusters as a way to produce more effective antifungal compounds -- Enzybiotics: The rush towards prevention and control of multi-resistant bacteria (MRB) -- New cell wall-affecting antifungal antibiotics -- Perspectives in the research on Antimicrobial peptides -- Glycopeptides and bacterial cell walls.
330   $aSince penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years. This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics.
606   $aMicrobiology
606   $aMedical microbiology
606   $aMicrobial genetics
606   $aMicrobial genomics
606   $aPharmaceutical technology
606   $aMicrobiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L23004
606   $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003
606   $aMicrobial Genetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32010
606   $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010
615  0$aMicrobiology.
615  0$aMedical microbiology.
615  0$aMicrobial genetics.
615  0$aMicrobial genomics.
615  0$aPharmaceutical technology.
615 14$aMicrobiology.
615 24$aMedical Microbiology.
615 24$aMicrobial Genetics and Genomics.
615 24$aPharmaceutical Sciences/Technology.
676   $a616.90461
702   $aVilla$b Tomás G$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aVeiga-Crespo$b Patricia$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298324903321
996   $aAntimicrobial Compounds$92500527
997   $aUNINA