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Titolo: | Gene therapy technologies, applications, and regulations : from laboratory to clinic / / edited by Anthony Meager |
Pubblicazione: | Chichester, West Sussex, England : , : John Wiley & Sons, Ltd, , 1999 |
©1999 | |
Descrizione fisica: | 1 online resource (439 p.) |
Disciplina: | 616.042 |
616/.042 | |
Soggetto topico: | Gene therapy |
Soggetto genere / forma: | Electronic books. |
Persona (resp. second.): | MeagerAnthony |
Note generali: | Description based upon print version of record. |
Nota di bibliografia: | Includes bibliographical references at the end of each chapters and index. |
Nota di contenuto: | Gene Therapy Technologies, Applications and Regulations; Contents; List of contributors; Preface; 1 Cationic Liposomes for Gene Therapy Applications; 2 DNA Condensation and Receptor-mediated Gene Transfer; 3 Retroviral Vectors; 4 Lentiviral Vectors; 5 Adenoviral Vectors; 6 Adeno-associated Viral Vectors; 7 Advances in Engineering HSV Vectors for Gene Transfer to the Nervous System; 8 Mammalian Artificial Chromosomes: Prospects for Gene Therapy; 9 Gene Therapy for Severe Combined Immunodeficiency; 10 Gene Therapy for Haemophilia; 11 Cystic Fibrosis: Gene Therapy Approaches |
12 Therapeutic Approaches to Haemoglobinopathies13 Gene Therapy Approaches to Duchenne Muscular Dystrophy; 14 Lysosomal Storage Diseases; 15 Prospects for Gene Therapy of HIV Infections and AIDS; 16 The Development of the Regulatory Process in Europe for Biological Medicines: how it Affects Gene Therapy Products; 17 Development and Regulation of Gene Therapy Drugs in Germany; 18 The Transfer of Technology from the Laboratory to the Clinic: In process Controls and Final Product Testing; 19 Good Laboratory Practice in the Research and Development Laboratory | |
20 Facilities for Large-scale Production of Vectors Under GMP ConditionsAddendum; Index | |
Sommario/riassunto: | Gene Therapy Technologies, Applications and Regulations From Laboratory to Clinic Edited by Anthony Meager Division of Immunobiology, The National Institute for Biological Standards and Control, South Mimms, UK The development of gene-based technologies has been rapid over the past decade and has consequently resulted in a surge of interest in human gene therapy, the deliberate transfer of genes to somatic cells to cure or alleviate disease symptoms. Hundreds of clinical protocols involving variously designed vectors for efficient gene transfer have been developed. However, the use of such com |
Titolo autorizzato: | Gene therapy technologies, applications, and regulations |
ISBN: | 1-280-55444-4 |
9786610554447 | |
0-470-35936-6 | |
0-470-84238-5 | |
0-470-85368-9 | |
Formato: | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910142484203321 |
Lo trovi qui: | Univ. Federico II |
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