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Mechanisms of Atrial Arrhythmias : Insights from the Development of a Biophysically Detailed Model of the Human Atria / / by Michael A. Colman



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Autore: Colman Michael A Visualizza persona
Titolo: Mechanisms of Atrial Arrhythmias : Insights from the Development of a Biophysically Detailed Model of the Human Atria / / by Michael A. Colman Visualizza cluster
Pubblicazione: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014
Edizione: 1st ed. 2014.
Descrizione fisica: 1 online resource (267 p.)
Disciplina: 616.1
Soggetto topico: Biophysics
Cardiology
Bioinformatics
Computational biology
Physics
Mathematical physics
Biological and Medical Physics, Biophysics
Computer Appl. in Life Sciences
Numerical and Computational Physics, Simulation
Mathematical Applications in the Physical Sciences
Note generali: Description based upon print version of record.
Nota di contenuto: Introduction -- Background -- Development of a new model for simulating the electrical action potentials of human atrial myocytes -- Development of a family of regional cell models -- Autonomic regulation and pathophysiological remodelling -- 3D Anatomical Modelling of the Atria -- Pacemaking and autonomic regulation in the 3D sinoatrial node and atria -- Atrial Fibrillation -- Discussion.
Sommario/riassunto: This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation.  The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial fibrillation and develops novel techniques for the monitoring of atrial tachycardia. .
Titolo autorizzato: Mechanisms of Atrial Arrhythmias  Visualizza cluster
ISBN: 3-319-01643-1
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910300377903321
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Serie: Springer Theses, Recognizing Outstanding Ph.D. Research, . 2190-5053