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[null,"1.","Record Nr.",null,"UNINA9910300377903321"]
[null,null,"Autore",null,"Colman Michael A"]
[null,null,"Titolo",null,"Mechanisms of Atrial Arrhythmias : Insights from the Development of a Biophysically Detailed Model of the Human Atria / / by Michael A. Colman"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014"]
[null,null,"ISBN",null,"3-319-01643-1"]
[null,null,"Edizione",null,"[1st ed. 2014.]"]
[null,null,"Descrizione fisica",null,"1 online resource (267 p.)"]
[null,null,"Collana",null,"Springer Theses, Recognizing Outstanding Ph.D. Research, , 2190-5053"]
[null,null,"Disciplina",null,"616.1"]
[null,null,"Soggetti",null,"Biophysics"]
[{"$nulls":4},"Cardiology"]
[{"$nulls":4},"Bioinformatics"]
[{"$nulls":4},"Computational biology"]
[{"$nulls":4},"Physics"]
[{"$nulls":4},"Mathematical physics"]
[{"$nulls":4},"Biological and Medical Physics, Biophysics"]
[{"$nulls":4},"Computer Appl. in Life Sciences"]
[{"$nulls":4},"Numerical and Computational Physics, Simulation"]
[{"$nulls":4},"Mathematical Applications in the Physical Sciences"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,"Nota di contenuto",null,"Introduction -- Background -- Development of a new model for simulating the electrical action potentials of human atrial myocytes -- Development of a family of regional cell models -- Autonomic regulation and pathophysiological remodelling -- 3D Anatomical Modelling of the Atria -- Pacemaking and autonomic regulation in the 3D sinoatrial node and atria -- Atrial Fibrillation -- Discussion."]
[null,null,null,"Sommario/riassunto","This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation.  The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial "]
[{"$nulls":4},"fibrillation and develops novel techniques for the monitoring of atrial tachycardia. ."]