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010   $a3-319-01643-1
024 7 $a10.1007/978-3-319-01643-6
035   $a(CKB)3710000000058108
035   $a(EBL)1592396
035   $a(OCoLC)902407356
035   $a(SSID)ssj0001067683
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035   $a(PQKBTitleCode)TC0001067683
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035   $a(MiAaPQ)EBC1592396
035   $a(DE-He213)978-3-319-01643-6
035   $a(PPN)176104526
035   $a(EXLCZ)993710000000058108
100   $a20131104d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aMechanisms of Atrial Arrhythmias $eInsights from the Development of a Biophysically Detailed Model of the Human Atria /$fby Michael A. Colman
205   $a1st ed. 2014.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2014.
215   $a1 online resource (267 p.)
225 1 $aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053
300   $aDescription based upon print version of record.
311   $a3-319-01642-3 
327   $aIntroduction -- Background -- Development of a new model for simulating the electrical action potentials of human atrial myocytes -- Development of a family of regional cell models -- Autonomic regulation and pathophysiological remodelling -- 3D Anatomical Modelling of the Atria -- Pacemaking and autonomic regulation in the 3D sinoatrial node and atria -- Atrial Fibrillation -- Discussion.
330   $aThis thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation.  The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial fibrillation and develops novel techniques for the monitoring of atrial tachycardia. .
410  0$aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053
606   $aBiophysics
606   $aBiophysics
606   $aCardiology
606   $aBioinformatics
606   $aComputational biology
606   $aPhysics
606   $aMathematical physics
606   $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008
606   $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037
606   $aComputer Appl. in Life Sciences$3https://scigraph.springernature.com/ontologies/product-market-codes/L17004
606   $aNumerical and Computational Physics, Simulation$3https://scigraph.springernature.com/ontologies/product-market-codes/P19021
606   $aMathematical Applications in the Physical Sciences$3https://scigraph.springernature.com/ontologies/product-market-codes/M13120
615  0$aBiophysics.
615  0$aBiophysics.
615  0$aCardiology.
615  0$aBioinformatics.
615  0$aComputational biology.
615  0$aPhysics.
615  0$aMathematical physics.
615 14$aBiological and Medical Physics, Biophysics.
615 24$aCardiology.
615 24$aComputer Appl. in Life Sciences.
615 24$aNumerical and Computational Physics, Simulation.
615 24$aMathematical Applications in the Physical Sciences.
676   $a616.1
700   $aColman$b Michael A$4aut$4http://id.loc.gov/vocabulary/relators/aut$0791369
906   $aBOOK
912   $a9910300377903321
996   $aMechanisms of Atrial Arrhythmias$91768752
997   $aUNINA