Experimental Research Methods in Orthopedics and Trauma / / by: Simpson, Hamish, Augat, Peter

• Autore: Rana Abou-Khalil
• Pubblicazione: Stuttgart, [Germany] : , : Thieme, , 2015; ©2015
• Descrizione fisica: 1 online resource (466 p.)
• Disciplina: 617.3
• Soggetto topico: Orthopedics; Musculoskeletal system; Medicine - Research
• Persona (resp. second.): SimpsonHamish; AugatPeter; AldridgeKishan Victoria; AldridgeRoland; AltVolker; AmisAndrew A; ArkelRichard <van>; BakkerAstrid D; BehrSpencer; BhattacharyaPinaki; BlokhuisTaco Johan; TorstenBlunk; BlunnGordon William; BorrelliJoseph; BravenboerNathalie; CheungWing-Hoi; Ho ChowSimon Kwoon; ClementNicholas; CoathupMelanie Jean; ColnotCéline; CristofoliniLuca; DannhornDieter R; DartonHannah; DijkgraafMarcel; DürselenLutz; EberleSebastian; EbertRegina; GelovenNan <van>; GoodshipAllen Edward; HaanRob de; HalewoodCamilla; HamiltonDavid; HankensonKurt D; HellerMarkus O; HenkenberensChristoph; HerfatSafa; HindlePaul; JackmanTimothy M; JakobFranz; JansenIneke D.C; JaspersRichard T; JenkinsPaul J; JosephGabby B; JufferPetra; KaddickChristian; KimGrace; JennekeKlein-Nulend; KlotzBarbara; LeeKwong-Man; LentheG. Harry <van>; LiXiaojuan; LieshoutEsther M.M. <van>; LinkThomas M; LuChuanyong; LumpaopongPunyawang; MacGillivrayThomas J; MarcucioRalph; McDonaldGabriel; MeierJeffrey; MentrupBirgit; MeulenMarjolein C. H. <van der>; MiclauTheodore; MillsLeanora Anne; MorganElise F; MurrayIain R; NiemeyerFrank; OldenburgGeert <von>; OxlandThomas R; PalBidyut; PankajPankaj; PathakJanak L; PendegrassCatherine Jane; RasmussenJohn; ReichertInes L.H; ReitsmaJohannes B; RichardsJim; RosenbaumDieter; RossErin; SchnettlerReinhard; SeitzAndreas Martin; SelfeJames; SempleScott Ian Kay; SimonUlrich; SmithInnes D M; SteinertAndre F; StephenJ.M; TanckMichael; VolkheimerDavid; WallaceRobert James; WestChristopher C; WilkeHans-Joachim; YosibashZohar; YuYan-Yiu
• Note generali: "257 illustrations."
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: Experimental Research Methods in Orthopedics and Trauma; Title Page; Copyright; Contents; Foreword; Endorsement by the International Combined Orthopaedic Research Societies (I-CORS) Member Organizations; Preface; Acknowledgments; Contributors; 1 Why Do We Need Experimental Research?; 1 Evidence-Based Research; 2 Establishing a Basic Research Facility in Orthopedic Surgery; 3 Good Laboratory Practice and Quality Control; 4 How to Prepare for a Period in Research; 2 Structural Biomechanics; 5 Physiological Boundary Conditions for Mechanical Testing ; 6 Static, Dynamic, and Fatigue Mechanical Testing7 Use of Human and Animal Specimens in Biomechanical Testing; 8 Whole Bone Biomechanics; 9 Biomechanics of Trabecular and Cortical Bone; 10 Biomechanics of Fracture Fixation; 11 Biomechanical Assessment of Fracture Repair; 12 Biomechanics of Cartilage; 13 Biomechanics of Joints; 14 Spine Biomechanics; 3 Functional Biomechanics; 15 Musculokeletal Dynamics; 16 Measurement Techniques; 17 Clinical Assessment of Function; 18 Functional Biomechanics with Cadaver Specimens; 4 Numerical Biomechanics; 19 Inverse Dynamics ; 20 Principles of Finite Elements Analysis21 Validation of Finite Element Models; 22 Computational Biomechanics of Bone; 23 Numerical Simulation of Implants and Prosthetic Devices; 24 Numerical Simulation of Fracture Healing and Bone Remodelling; 5 Imaging; 25 Micro-Computed Tomography Imaging of Bone Tissue; 26 Imaging Bone; 27 Ultrasound Techniques for Imaging Bone; 28 In Vivo Scanning; 29 Imaging of Cartilage Function; 30 Histochemistry Bone and Cartilage; 31 Immunohistochemistry; 32 Molecular Imaging In Situ Hybridization; 33 Laser Scanning Confocal Microscopy and Laser Microdissection ; 34 Image Analysis Histomorphometry Stereology6 Cellular Studies; 35 Cell Culture Research; 36 Cartilage Explants and Organ Culture Models; 37 Fluid Flow and Strain in Bone; 38 Biomechanics of Bone Cells; 7 Molecular Techniques in Bone Repair; 39 Molecular Testing; 40 Genetically Modified Models for Bone Repair; 8 In Vivo Models; 41 General Considerations for an In Vivo Model; 42 Animal Models for Bone Healing; 43 Models for Impaired Healing; 44 In Vivo Models for Bone and Joint Infections; 45 In Vivo Models for Articular Cartilage Repair; 46 In Vivo Soft Tissue Models; 9 Tissue Engineering ; 47 Scaffolds for Tissue Engineering and Materials for Repair48 Use of Growth Factors in Musculoskeletal Research; 49 Stem Cells for Musculoskeletal Repair; 50 Biological Evaluation and Testing of Medical Devices; 10 Statistics for Experimental Research; 51 Study Design; 52 Power and Sample Size Calculation; 53 Nonparametric versus Parametric Tests; 54 How to Limit Bias in Experimental Research; Index
• Sommario/riassunto: From bioinformatics to nanotechnology, advances in basic research ultimately drive advances in clinical care. This book provides a comprehensive summary of all current research methodologies for translational and pre-clinical studies in biomechanics and orthopedic trauma surgery. With this roadmap at hand, specialists and trainees will have the tools to conduct high-quality experimental research in any area of musculoskeletal science, with a solid understanding of how the findings can be applied in patient care. Special Features: Utilizes the principles and methodology of modern, evidence-bas
• Titolo autorizzato: Experimental Research Methods in Orthopedics and Trauma
• ISBN: 3-13-258147-X
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910825228603321
• Lo trovi qui: Univ. Federico II