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INDIANO - LETTERATURE DRAVIDICHE MINORI - MALAYALAM$2A 700 1$aSUNDARAM$bDhanuvachapuram$3UONV084376$0670950 801 $aIT$bSOL$c20240220$gRICA 899 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$2UONSI 912 $aUON00138890 950 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$dSI SI VI MM 284 $eSI SA 58044 5 284 996 $aKannippukkal$91279948 997 $aUNIOR LEADER 13069nam 2201789 450 001 9910825228603321 005 20230731071714.0 010 $a3-13-258147-X 024 7 $a10.1055/b-003-121999 035 $a(CKB)3880000000003606 035 $a(EBL)2078422 035 $a(SSID)ssj0001517058 035 $a(PQKBManifestationID)12589707 035 $a(PQKBTitleCode)TC0001517058 035 $a(PQKBWorkID)11499884 035 $a(PQKB)11404788 035 $a(Au-PeEL)EBL2078422 035 $a(CaPaEBR)ebr11071284 035 $a(CaONFJC)MIL803992 035 $a(OCoLC)913335802 035 $a10.1055-b-003-121999 035 $a(DE-2912)1496448426599 035 $a(MiAaPQ)EBC2078422 035 $a(EXLCZ)993880000000003606 100 $a20150711h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aExperimental Research Methods in Orthopedics and Trauma /$fby: Simpson, Hamish, Augat, Peter 210 1$aStuttgart, [Germany] :$cThieme,$d2015. 210 4$d©2015 215 $a1 online resource (466 p.) 300 $a"257 illustrations." 311 $a3-13-173111-7 311 $a3-13-173121-4 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aExperimental Research Methods in Orthopedics and Trauma; Title Page; Copyright; Contents; Foreword; Endorsement by the International Combined Orthopaedic Research Societies (I-CORS) Member Organizations; Preface; Acknowledgments; Contributors; 1 Why Do We Need Experimental Research?; 1 Evidence-Based Research; 2 Establishing a Basic Research Facility in Orthopedic Surgery; 3 Good Laboratory Practice and Quality Control; 4 How to Prepare for a Period in Research; 2 Structural Biomechanics; 5 Physiological Boundary Conditions for Mechanical Testing 327 $a6 Static, Dynamic, and Fatigue Mechanical Testing7 Use of Human and Animal Specimens in Biomechanical Testing; 8 Whole Bone Biomechanics; 9 Biomechanics of Trabecular and Cortical Bone; 10 Biomechanics of Fracture Fixation; 11 Biomechanical Assessment of Fracture Repair; 12 Biomechanics of Cartilage; 13 Biomechanics of Joints; 14 Spine Biomechanics; 3 Functional Biomechanics; 15 Musculokeletal Dynamics; 16 Measurement Techniques; 17 Clinical Assessment of Function; 18 Functional Biomechanics with Cadaver Specimens; 4 Numerical Biomechanics; 19 Inverse Dynamics 327 $a20 Principles of Finite Elements Analysis21 Validation of Finite Element Models; 22 Computational Biomechanics of Bone; 23 Numerical Simulation of Implants and Prosthetic Devices; 24 Numerical Simulation of Fracture Healing and Bone Remodelling; 5 Imaging; 25 Micro-Computed Tomography Imaging of Bone Tissue; 26 Imaging Bone; 27 Ultrasound Techniques for Imaging Bone; 28 In Vivo Scanning; 29 Imaging of Cartilage Function; 30 Histochemistry Bone and Cartilage; 31 Immunohistochemistry; 32 Molecular Imaging In Situ Hybridization; 33 Laser Scanning Confocal Microscopy and Laser Microdissection 327 $a34 Image Analysis Histomorphometry Stereology6 Cellular Studies; 35 Cell Culture Research; 36 Cartilage Explants and Organ Culture Models; 37 Fluid Flow and Strain in Bone; 38 Biomechanics of Bone Cells; 7 Molecular Techniques in Bone Repair; 39 Molecular Testing; 40 Genetically Modified Models for Bone Repair; 8 In Vivo Models; 41 General Considerations for an In Vivo Model; 42 Animal Models for Bone Healing; 43 Models for Impaired Healing; 44 In Vivo Models for Bone and Joint Infections; 45 In Vivo Models for Articular Cartilage Repair; 46 In Vivo Soft Tissue Models; 9 Tissue Engineering 327 $a47 Scaffolds for Tissue Engineering and Materials for Repair48 Use of Growth Factors in Musculoskeletal Research; 49 Stem Cells for Musculoskeletal Repair; 50 Biological Evaluation and Testing of Medical Devices; 10 Statistics for Experimental Research; 51 Study Design; 52 Power and Sample Size Calculation; 53 Nonparametric versus Parametric Tests; 54 How to Limit Bias in Experimental Research; Index 330 $aFrom bioinformatics to nanotechnology, advances in basic research ultimately drive advances in clinical care. This book provides a comprehensive summary of all current research methodologies for translational and pre-clinical studies in biomechanics and orthopedic trauma surgery. With this roadmap at hand, specialists and trainees will have the tools to conduct high-quality experimental research in any area of musculoskeletal science, with a solid understanding of how the findings can be applied in patient care. 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