Paradox Role of Oxidative Stress in Cancer : State of the Art

• Autore: Domenicotti Cinzia
• Pubblicazione: Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
• Descrizione fisica: 1 online resource (214 p.)
• Soggetto topico: Medicine and Nursing; Oncology
• Soggetto non controllato: antitumor agents; apoptosis; bioinorganic chemistry; biomarker; breast cancer treatment; cancer progression; cancer stem cells; cancer therapy; cancer treatment; cancerogenesis; carbon doped titanium dioxide; chemoresistance; cold atmospheric plasma; combined treatment; coordination polymers; DNA damage; Eprenetapopt; Erastin; ferroptosis; glutathione; glutathione (GSH); GPX4; hematological malignancies; HO-1; hyperforin; Hypericum perforatum; immune system; inflammatory signaling; iron; leukemia; lipid peroxidation; lymphoma; mitochondria; multiple myeloma; n/a; natural compounds; nitrite; Nrf2; NRF2; oral cancer; oxidative stress; pancreatic cancer; patients; pH regulation; prognosis; radiotherapy; reactive oxygen and nitrogen species; reactive oxygen species; SLC7A11; sonodynamic therapy; sonosensitizers; therapy; tumor prevention; tumor therapy; ultrasound; ultraviolet-C (UVC); withanolide; ZEB-1
• Persona (resp. second.): MarengoBarbara; DomenicottiCinzia
• Sommario/riassunto: Reactive oxygen species (ROS) are produced by healthy cells and are maintained at physiological levels by antioxidant systems. However, when ROS increase in number, a condition of oxidative stress occurs, leading to many human diseases, including cancer. The relationship between oxidative stress and cancer is complex since ROS play a double-edged role in cancer development and under therapy response. This paradox represents a great challenge for researchers and needs to be investigated. The articles collected in this Special Issue can help to clarify the role of ROS modulation in cancer prevention and treatment, and to dissect the molecular mechanisms underlying its paradoxical role in order to counteract carcinogenesis or enhance sensitivity to anticancer therapy.
• Altri titoli varianti: Paradox Role of Oxidative Stress in Cancer
• Titolo autorizzato: Paradox Role of Oxidative Stress in Cancer
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910580205303321
• Lo trovi qui: Univ. Federico II