LEADER 03815nam 2201093z- 450 001 9910580205303321 005 20220706 035 $a(CKB)5690000000012035 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/87477 035 $a(oapen)doab87477 035 $a(EXLCZ)995690000000012035 100 $a20202207d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aParadox Role of Oxidative Stress in Cancer$eState of the Art 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (214 p.) 311 08$a3-0365-4421-6 311 08$a3-0365-4422-4 330 $aReactive oxygen species (ROS) are produced by healthy cells and are maintained at physiological levels by antioxidant systems. However, when ROS increase in number, a condition of oxidative stress occurs, leading to many human diseases, including cancer. The relationship between oxidative stress and cancer is complex since ROS play a double-edged role in cancer development and under therapy response. This paradox represents a great challenge for researchers and needs to be investigated. The articles collected in this Special Issue can help to clarify the role of ROS modulation in cancer prevention and treatment, and to dissect the molecular mechanisms underlying its paradoxical role in order to counteract carcinogenesis or enhance sensitivity to anticancer therapy. 517 $aParadox Role of Oxidative Stress in Cancer 606 $aMedicine and Nursing$2bicssc 606 $aOncology$2bicssc 610 $aantitumor agents 610 $aapoptosis 610 $abioinorganic chemistry 610 $abiomarker 610 $abreast cancer treatment 610 $acancer progression 610 $acancer stem cells 610 $acancer therapy 610 $acancer treatment 610 $acancerogenesis 610 $acarbon doped titanium dioxide 610 $achemoresistance 610 $acold atmospheric plasma 610 $acombined treatment 610 $acoordination polymers 610 $aDNA damage 610 $aEprenetapopt 610 $aErastin 610 $aferroptosis 610 $aglutathione 610 $aglutathione (GSH) 610 $aGPX4 610 $ahematological malignancies 610 $aHO-1 610 $ahyperforin 610 $aHypericum perforatum 610 $aimmune system 610 $ainflammatory signaling 610 $airon 610 $aleukemia 610 $alipid peroxidation 610 $alymphoma 610 $amitochondria 610 $amultiple myeloma 610 $an/a 610 $anatural compounds 610 $anitrite 610 $aNrf2 610 $aNRF2 610 $aoral cancer 610 $aoxidative stress 610 $apancreatic cancer 610 $apatients 610 $apH regulation 610 $aprognosis 610 $aradiotherapy 610 $areactive oxygen and nitrogen species 610 $areactive oxygen species 610 $aSLC7A11 610 $asonodynamic therapy 610 $asonosensitizers 610 $atherapy 610 $atumor prevention 610 $atumor therapy 610 $aultrasound 610 $aultraviolet-C (UVC) 610 $awithanolide 610 $aZEB-1 615 7$aMedicine and Nursing 615 7$aOncology 700 $aDomenicotti$b Cinzia$4edt$01329334 702 $aMarengo$b Barbara$4edt 702 $aDomenicotti$b Cinzia$4oth 702 $aMarengo$b Barbara$4oth 906 $aBOOK 912 $a9910580205303321 996 $aParadox Role of Oxidative Stress in Cancer$93039443 997 $aUNINA LEADER 04410nam 2201069z- 450 001 9910557611503321 005 20220321 035 $a(CKB)5400000000045287 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/79620 035 $a(oapen)doab79620 035 $a(EXLCZ)995400000000045287 100 $a20202203d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aManaging the Product Quality of Vegetable Crops under Abiotic Stress 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (168 p.) 311 08$a3-0365-3098-3 311 08$a3-0365-3099-1 330 $aVegetables are an important part of the human diet due to their nutrient density and, at the same time, low calorie content. Producers of vegetable crops mainly aim at achieving high yields with good external quality. However, there is an increasing demand of consumers for vegetables that provide good sensory properties and are rich in secondary compounds that can be valuable for human health. Sub- or supra-optimal abiotic conditions, like high temperatures, drought, excess light, salinity or nutrient deficiency, may alter the composition of vegetable crops and at the same time, result in yield loss. Thus, producers need to adapt their horticultural practices such as through the choice of variety, irrigation regime, light management, fruit thinning, or fertilizer application to improve the yield and quality of the vegetable product. In the future, altered climate conditions such as elevated atmospheric CO2 concentrations, rising temperatures, or altered precipitation patterns may become additional challenges for producers of vegetable crops, especially those that cultivate in the open field. This raises the need for optimized horticultural practices in order to minimize abiotic stresses. As well, specific storage conditions can have large impacts on the quality of vegetables. This Special Issue compiles research that deals with the optimization of vegetable product quality (e.g. sensory aspects, composition) under sub- or supra-optimal abiotic conditions. 606 $aResearch & information: general$2bicssc 610 $aabiotic stress 610 $aAllium cepa 610 $aammonium 610 $aantioxidants 610 $aascorbic acid 610 $abiostimulants 610 $acarotenoids 610 $acatalase 610 $aclimate change 610 $adismutase 610 $aDPPH 610 $adrought 610 $adrought potassium 610 $aelevated CO? 610 $afatty acids 610 $aflesh firmness 610 $aflowering 610 $afood quality 610 $agibberex 610 $agrafting 610 $aharvest time 610 $aheirloom beans 610 $aLambada and Red Bone 610 $alocal farming 610 $alycopene 610 $aminerals 610 $amodified atmosphere package 610 $aMomordica charantia L 610 $an/a 610 $aNaCl 610 $aNasarpuri 610 $anitrate 610 $anitrogen 610 $anitrogen source 610 $anutraceutical properties 610 $anutrient use efficiency 610 $aOcimum basilicum 610 $aoxalate 610 $aperoxidase 610 $aphotosynthesis 610 $aPhulkara 610 $aphytochemicals 610 $apolyphenols 610 $aproduct quality 610 $aquality 610 $arootstock-scion combination 610 $asalt 610 $asensory and physiological-biochemical characteristics 610 $ashelf life 610 $aSolanum lycopersicum 610 $ataste 610 $atomato 610 $atotal phenol 610 $atotal soluble solids 610 $avacuolar transporter 610 $avegetable 610 $avegetable production 610 $avegetative growth 610 $awater-use efficiency 610 $ayield 610 $azinc 615 7$aResearch & information: general 700 $aSchmidt$b Lilian$4edt$01319400 702 $aSchmidt$b Lilian$4oth 906 $aBOOK 912 $a9910557611503321 996 $aManaging the Product Quality of Vegetable Crops under Abiotic Stress$93033879 997 $aUNINA