Vai al contenuto principale della pagina

Amide Bond Activation



(Visualizza in formato marc)    (Visualizza in BIBFRAME)

Autore: Szostak Michal Visualizza persona
Titolo: Amide Bond Activation Visualizza cluster
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute, 2019
Descrizione fisica: 1 electronic resource (466 p.)
Soggetto non controllato: N-heterocyclic carbene
non planar amide
ruthenium (Ru)
physical organic chemistry
gemcitabine prodrug
pyramidal amides
bridged sultams
catalysis
dipeptides
N-(1-naphthyl)acetamide
C-N ? bond cleavage
steric effects
peptide bond cleavage
transition-metal-free
palladium
N-heterocyclic carbenes (NHCs)
addition reaction
C–O activation
rhodium
metal complexes
carbanions
thioamidation
amide bond
intramolecular catalysis
antiviral activity
additivity principle
pre-catalysts
C–N bond cleavage
bridged lactams
C–H acidity
arynes
twisted amides
organic synthesis
amination
Suzuki-Miyaura
tert-butyl
cyclopentadienyl complexes
C-S formation
enzymes
DFT study
sulfonamide bond
N
HERON reaction
primaquine
entropy
amide activation
amidation
synthesis
amide hydrolysis
carbonylicity
amide bond activation
amide bond resonance
aminosulfonylation
molecular dynamics
model compound
in situ
amide
homogeneous catalysis
heterocycles
anomeric effect
multi-component coupling reaction
kinetic
excited state
C–H bond cleavage
palladium catalysis
amides
thiourea
formylation
alkynes
cis/trans isomerization
amide C–N bond activation
intein
C-H functionalization
succindiamide
amide bonds
crown ether
aminoacylation
directing groups
cytostatic activity
reaction thermodynamics
acyl transfer
transition metals
N-dimethylformamide
DMAc
acylative cross-coupling
C-H/C-N activation
nickel catalysis
antibacterial screening
sodium
aryl thioamides
Winkler-Dunitz parameters
catalyst
N-dimethylacetamide
base-catalyed hydrolysis
nitrogen heterocycles
cross-coupling
insertion
amidicity
nitro-aci tautomerism
activation
carbonylation
transamidation
amine
distortion
Pd-catalysis
rotational barrier energy
hypersensitivity
N–C activation
metabolic stability
[2+2+2] annulation
twisted amide
protease
cyanation
amide resonance
trialkylborane
catalysts
biofilm eradication
pharmacokinetics
pancreatic cancer cells
DMF
aryl esters
Michael acceptor
fumardiamide
water solvation
ester bond activation
cyclization
nuclear magnetic resonance
secondary amides
reaction mechanism
density functional theory
density-functional theory
amino acid transporters
Sommario/riassunto: The amide bond represents a privileged motif in chemistry. The recent years have witnessed an explosion of interest in the development of new chemical transformations of amides. These developments cover an impressive range of catalytic N–C bond activation in electrophilic, Lewis acid, radical, and nucleophilic reaction pathways, among other transformations. Equally relevant are structural and theoretical studies that provide the basis for chemoselective manipulation of amidic resonance. This monograph on amide bonds offers a broad survey of recent advances in activation of amides and addresses various approaches in the field.
Titolo autorizzato: Amide Bond Activation  Visualizza cluster
ISBN: 3-03921-204-4
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910346843703321
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui