LEADER 05721nam 2201873z- 450 001 9910346843703321 005 20231214133001.0 010 $a3-03921-204-4 035 $a(CKB)4920000000095203 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/40763 035 $a(EXLCZ)994920000000095203 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAmide Bond Activation 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 215 $a1 electronic resource (466 p.) 311 $a3-03921-203-6 330 $aThe amide bond represents a privileged motif in chemistry. The recent years have witnessed an explosion of interest in the development of new chemical transformations of amides. These developments cover an impressive range of catalytic N?C bond activation in electrophilic, Lewis acid, radical, and nucleophilic reaction pathways, among other transformations. Equally relevant are structural and theoretical studies that provide the basis for chemoselective manipulation of amidic resonance. This monograph on amide bonds offers a broad survey of recent advances in activation of amides and addresses various approaches in the field. 610 $aN-heterocyclic carbene 610 $anon planar amide 610 $aruthenium (Ru) 610 $aphysical organic chemistry 610 $agemcitabine prodrug 610 $apyramidal amides 610 $abridged sultams 610 $acatalysis 610 $adipeptides 610 $aN-(1-naphthyl)acetamide 610 $aC-N ? bond cleavage 610 $asteric effects 610 $apeptide bond cleavage 610 $atransition-metal-free 610 $apalladium 610 $aN-heterocyclic carbenes (NHCs) 610 $aaddition reaction 610 $aC?O activation 610 $arhodium 610 $ametal complexes 610 $acarbanions 610 $athioamidation 610 $aamide bond 610 $aintramolecular catalysis 610 $aantiviral activity 610 $aadditivity principle 610 $apre-catalysts 610 $aC?N bond cleavage 610 $abridged lactams 610 $aC?H acidity 610 $aarynes 610 $atwisted amides 610 $aorganic synthesis 610 $aamination 610 $aSuzuki-Miyaura 610 $atert-butyl 610 $acyclopentadienyl complexes 610 $aC-S formation 610 $aenzymes 610 $aDFT study 610 $asulfonamide bond 610 $aN 610 $aHERON reaction 610 $aprimaquine 610 $aentropy 610 $aamide activation 610 $aamidation 610 $asynthesis 610 $aamide hydrolysis 610 $acarbonylicity 610 $aamide bond activation 610 $aamide bond resonance 610 $aaminosulfonylation 610 $amolecular dynamics 610 $amodel compound 610 $ain situ 610 $aamide 610 $ahomogeneous catalysis 610 $aheterocycles 610 $aanomeric effect 610 $amulti-component coupling reaction 610 $akinetic 610 $aexcited state 610 $aC?H bond cleavage 610 $apalladium catalysis 610 $aamides 610 $athiourea 610 $aformylation 610 $aalkynes 610 $acis/trans isomerization 610 $aamide C?N bond activation 610 $aintein 610 $aC-H functionalization 610 $asuccindiamide 610 $aamide bonds 610 $acrown ether 610 $aaminoacylation 610 $adirecting groups 610 $acytostatic activity 610 $areaction thermodynamics 610 $aacyl transfer 610 $atransition metals 610 $aN-dimethylformamide 610 $aDMAc 610 $aacylative cross-coupling 610 $aC-H/C-N activation 610 $anickel catalysis 610 $aantibacterial screening 610 $asodium 610 $aaryl thioamides 610 $aWinkler-Dunitz parameters 610 $acatalyst 610 $aN-dimethylacetamide 610 $abase-catalyed hydrolysis 610 $anitrogen heterocycles 610 $across-coupling 610 $ainsertion 610 $aamidicity 610 $anitro-aci tautomerism 610 $aactivation 610 $acarbonylation 610 $atransamidation 610 $aamine 610 $adistortion 610 $aPd-catalysis 610 $arotational barrier energy 610 $ahypersensitivity 610 $aN?C activation 610 $ametabolic stability 610 $a[2+2+2] annulation 610 $atwisted amide 610 $aprotease 610 $acyanation 610 $aamide resonance 610 $atrialkylborane 610 $acatalysts 610 $abiofilm eradication 610 $apharmacokinetics 610 $apancreatic cancer cells 610 $aDMF 610 $aaryl esters 610 $aMichael acceptor 610 $afumardiamide 610 $awater solvation 610 $aester bond activation 610 $acyclization 610 $anuclear magnetic resonance 610 $asecondary amides 610 $areaction mechanism 610 $adensity functional theory 610 $adensity-functional theory 610 $aamino acid transporters 700 $aSzostak$b Michal$4auth$01302835 906 $aBOOK 912 $a9910346843703321 996 $aAmide Bond Activation$93026673 997 $aUNINA