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Genome Mining and Marine Microbial Natural Products



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Autore: Hong Kui Visualizza persona
Titolo: Genome Mining and Marine Microbial Natural Products Visualizza cluster
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute, 2020
Descrizione fisica: 1 online resource (202 p.)
Soggetto topico: Biology, life sciences
Soggetto non controllato: 16S rRNA metagenomics
actinobacteria
amino compound
Antarctica
antibacterial
antibacterial activity
antifungal
antimicrobial
antimicrobial activity
archaea
bacillibactin
bacillomycin
biosynthesis
biosynthetic gene clusters
carotenoid
comparative genomics
cytotoxicity
drug discovery
ecotype
fatty acid amide
fibrinolytic activity
gene cluster
genome mining
halo-extremophyles
haloenzymes
histone-deacetylase inhibitor
IclR family regulator
isoindolinone biosynthesis
marine
marine Bacillus
marine microorganisms
marine natural product
marine natural products (MNPs)
Marisediminicola
medicinal chemistry
meroterpenoid
metal stress technique
natural products
NdgRyo
nonribosomal peptides
Odiel marshlands
Penicillium chrysogenum
phylotype
polycyclic tetramate macrolactams
polyketide antibiotics
polyketide synthase
secondary metabolites
sponge
Stachybotrys
Streptomyces
Streptomyces pratensis
Streptomyces sp. SCSIO 40010
Persona (resp. second.): ZhangChangsheng
DobsonAlan
Sommario/riassunto: Two review papers, eight research articles, and one brief report were published in this Special Issue. They showed the rich resources that are present within the genomes of marine microorganisms and discussed the use of recently developed tools and technologies to exploit this genetic richness. Examples include the rational supply of precursors according to the relevant biosynthetic pathway and stress driven discovery together with the use of histone deacetylase inhibitors to facilitate the discovery of new bioactive molecules with potential biopharmaceutical applications. We believe that the content of this Special Issue reflects the current state-of-the-art research in this area and highlights the interesting strategies that are being employed to uncover increasing numbers of exciting novel compounds for drug discovery from marine genetic resources.
Titolo autorizzato: Genome Mining and Marine Microbial Natural Products  Visualizza cluster
ISBN: 3-03928-091-0
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910372785703321
Lo trovi qui: Univ. Federico II
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