Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications

• Autore: Doti Nunzianna
• Pubblicazione: Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
• Descrizione fisica: 1 online resource (274 p.)
• Soggetto topico: Biology, life sciences; Research & information: general
• Soggetto non controllato: AFM; AIF(370-394) peptide; ALOS4; amphiphilic peptides; antibacterial; anticancer peptides; antifungal; antimicrobial peptide; antimicrobial peptides; antiproliferative activity; antitumor peptide; antiviral; apoptosis-inducing factor (AIF); Aβ; cancer; caspase-3; chirality; conformational analysis; cyclic peptide; cyclophilin A (CypA); deferoxamine; density functional theory (DFT); diagnostic; drug delivery; drug repurposing; ELISA; environment-sensitive fluorophore; ferrocene; fibroblast growth factor 14 (FGF14); fluorescent peptide; FRET; human neuroblastoma SH-SY5Y cells; hydrocarbon stapling; hydrogen bonds; i,i + 1 staple; IAPP; imaging diagnostic; integrin; integrins; luciferin; medium spiny neurons (MSNs); melanoma; membrane-binding peptide; microarray; MM-GBSA; molecular docking; molecular dynamics; molecular modelling; nanocarrier; neurotherapeutics; non-imaging diagnostic; non-viral gene delivery; nucleus accumbens (NAc); PARP; peptide; peptide antigens; peptide labeling; peptide self-assemblies; peptide-based therapies; peptides; peptidomimetic; peptidomimetics; PET; PET imaging; polymers; protein-protein interactions (PPIs); radiodiagnostics; retro-inverso peptides; RGD peptide; RGD peptides; ring-closing metathesis; SARS-CoV-2; SPECT; staurosporine-mediated cell death; stimuli responsive; synthetic peptides; transfection; voltage-gated Na+ (Nav) channels; X-ray; X-ray structure; α-helix; αvβ3
• Persona (resp. second.): RuvoMenotti; DotiNunzianna
• Sommario/riassunto: This Special Issue, entitled "Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications", has included both reviews and original research contributions focused on the chemical design and biomedical applications of structurally modified bioactive peptides. The papers collected show how successful this class of molecules still is, both as model molecules for studying the structure of proteins and as potential therapeutics and diagnostics, and also as laboratory tools for advanced basic and applied studies. The large scientific community working in this field is in fact very active and productive, and is making the most of the potential and versatility of these molecules to generate increasingly interesting and innovative molecules of therapeutic interest and to understand the fundamental molecular mechanisms of life.
• Altri titoli varianti: Synthetic Peptides and Peptidomimetics
• Titolo autorizzato: Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910580210803321
• Lo trovi qui: Univ. Federico II