LEADER 04873nam 2201381z- 450 001 9910580210803321 005 20220706 035 $a(CKB)5690000000011980 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/87450 035 $a(oapen)doab87450 035 $a(EXLCZ)995690000000011980 100 $a20202207d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aSynthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (274 p.) 311 08$a3-0365-4396-1 311 08$a3-0365-4395-3 330 $aThis Special Issue, entitled "Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications", has included both reviews and original research contributions focused on the chemical design and biomedical applications of structurally modified bioactive peptides. The papers collected show how successful this class of molecules still is, both as model molecules for studying the structure of proteins and as potential therapeutics and diagnostics, and also as laboratory tools for advanced basic and applied studies. The large scientific community working in this field is in fact very active and productive, and is making the most of the potential and versatility of these molecules to generate increasingly interesting and innovative molecules of therapeutic interest and to understand the fundamental molecular mechanisms of life. 517 $aSynthetic Peptides and Peptidomimetics 606 $aBiology, life sciences$2bicssc 606 $aResearch & information: general$2bicssc 610 $aAFM 610 $aAIF(370-394) peptide 610 $aALOS4 610 $aamphiphilic peptides 610 $aantibacterial 610 $aanticancer peptides 610 $aantifungal 610 $aantimicrobial peptide 610 $aantimicrobial peptides 610 $aantiproliferative activity 610 $aantitumor peptide 610 $aantiviral 610 $aapoptosis-inducing factor (AIF) 610 $aA? 610 $acancer 610 $acaspase-3 610 $achirality 610 $aconformational analysis 610 $acyclic peptide 610 $acyclophilin A (CypA) 610 $adeferoxamine 610 $adensity functional theory (DFT) 610 $adiagnostic 610 $adrug delivery 610 $adrug repurposing 610 $aELISA 610 $aenvironment-sensitive fluorophore 610 $aferrocene 610 $afibroblast growth factor 14 (FGF14) 610 $afluorescent peptide 610 $aFRET 610 $ahuman neuroblastoma SH-SY5Y cells 610 $ahydrocarbon stapling 610 $ahydrogen bonds 610 $ai,i + 1 staple 610 $aIAPP 610 $aimaging diagnostic 610 $aintegrin 610 $aintegrins 610 $aluciferin 610 $amedium spiny neurons (MSNs) 610 $amelanoma 610 $amembrane-binding peptide 610 $amicroarray 610 $aMM-GBSA 610 $amolecular docking 610 $amolecular dynamics 610 $amolecular modelling 610 $ananocarrier 610 $aneurotherapeutics 610 $anon-imaging diagnostic 610 $anon-viral gene delivery 610 $anucleus accumbens (NAc) 610 $aPARP 610 $apeptide 610 $apeptide antigens 610 $apeptide labeling 610 $apeptide self-assemblies 610 $apeptide-based therapies 610 $apeptides 610 $apeptidomimetic 610 $apeptidomimetics 610 $aPET 610 $aPET imaging 610 $apolymers 610 $aprotein-protein interactions (PPIs) 610 $aradiodiagnostics 610 $aretro-inverso peptides 610 $aRGD peptide 610 $aRGD peptides 610 $aring-closing metathesis 610 $aSARS-CoV-2 610 $aSPECT 610 $astaurosporine-mediated cell death 610 $astimuli responsive 610 $asynthetic peptides 610 $atransfection 610 $avoltage-gated Na+ (Nav) channels 610 $aX-ray 610 $aX-ray structure 610 $a?-helix 610 $a?v?3 615 7$aBiology, life sciences 615 7$aResearch & information: general 700 $aDoti$b Nunzianna$4edt$01332309 702 $aRuvo$b Menotti$4edt 702 $aDoti$b Nunzianna$4oth 702 $aRuvo$b Menotti$4oth 906 $aBOOK 912 $a9910580210803321 996 $aSynthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications$93040812 997 $aUNINA