LEADER 04858nam 2201369z- 450 001 9910580210803321 005 20231214133432.0 035 $a(CKB)5690000000011980 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/87450 035 $a(EXLCZ)995690000000011980 100 $a20202207d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSynthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (274 p.) 311 $a3-0365-4396-1 311 $a3-0365-4395-3 330 $aThis Special Issue, entitled "Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications", has included both reviews and original research contributions focused on the chemical design and biomedical applications of structurally modified bioactive peptides. The papers collected show how successful this class of molecules still is, both as model molecules for studying the structure of proteins and as potential therapeutics and diagnostics, and also as laboratory tools for advanced basic and applied studies. The large scientific community working in this field is in fact very active and productive, and is making the most of the potential and versatility of these molecules to generate increasingly interesting and innovative molecules of therapeutic interest and to understand the fundamental molecular mechanisms of life. 517 $aSynthetic Peptides and Peptidomimetics 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $apolymers 610 $apeptidomimetics 610 $aAFM 610 $atransfection 610 $amolecular modelling 610 $apeptide 610 $a?-helix 610 $ahydrocarbon stapling 610 $aring-closing metathesis 610 $ai,i + 1 staple 610 $aX-ray structure 610 $adeferoxamine 610 $aRGD peptides 610 $aintegrins 610 $aradiodiagnostics 610 $aPET imaging 610 $aretro-inverso peptides 610 $aanticancer peptides 610 $adrug delivery 610 $apeptide antigens 610 $aA? 610 $aIAPP 610 $aantimicrobial peptides 610 $apeptides 610 $adiagnostic 610 $aELISA 610 $amicroarray 610 $aPET 610 $aSPECT 610 $aimaging diagnostic 610 $anon-imaging diagnostic 610 $aamphiphilic peptides 610 $anon-viral gene delivery 610 $ananocarrier 610 $apeptide self-assemblies 610 $astimuli responsive 610 $aSARS-CoV-2 610 $aFRET 610 $amolecular docking 610 $amolecular dynamics 610 $aMM-GBSA 610 $adrug repurposing 610 $aantiviral 610 $acancer 610 $acyclic peptide 610 $aintegrin 610 $a?v?3 610 $aALOS4 610 $amelanoma 610 $afluorescent peptide 610 $aenvironment-sensitive fluorophore 610 $apeptide labeling 610 $aluciferin 610 $amembrane-binding peptide 610 $aantimicrobial peptide 610 $aantitumor peptide 610 $aRGD peptide 610 $aantiproliferative activity 610 $achirality 610 $aconformational analysis 610 $adensity functional theory (DFT) 610 $aferrocene 610 $ahydrogen bonds 610 $apeptidomimetic 610 $aX-ray 610 $aprotein?protein interactions (PPIs) 610 $avoltage-gated Na+ (Nav) channels 610 $afibroblast growth factor 14 (FGF14) 610 $amedium spiny neurons (MSNs) 610 $anucleus accumbens (NAc) 610 $aneurotherapeutics 610 $acyclophilin A (CypA) 610 $aapoptosis-inducing factor (AIF) 610 $ahuman neuroblastoma SH-SY5Y cells 610 $astaurosporine-mediated cell death 610 $aAIF(370-394) peptide 610 $acaspase-3 610 $aPARP 610 $aantifungal 610 $aantibacterial 610 $apeptide-based therapies 610 $asynthetic peptides 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aDoti$b Nunzianna$4edt$01332309 702 $aRuvo$b Menotti$4edt 702 $aDoti$b Nunzianna$4oth 702 $aRuvo$b Menotti$4oth 906 $aBOOK 912 $a9910580210803321 996 $aSynthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications$93040812 997 $aUNINA