The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease

• Autore: Chung Hae-Young
• Pubblicazione: Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
• Descrizione fisica: 1 online resource (186 p.)
• Soggetto topico: Biology, life sciences; Cultural studies: food and society; Research and information: general
• Soggetto non controllato: adipocyte; adiponectin; aging; autophagy; body mass reduction; calcium transient proteins; caloric restriction; calorie restriction; calorie restriction (CR); calorie restriction diet; CR mimetic; fasting; fat mass; fatty acid biosynthesis; FoxO transcription factor; heart impairment; IGF-1; insulin; insulin secretion; intermittent fasting; L-type calcium channel; leptin; lifespan; longevity; malnutrition; mimetics; mitochondrial biogenesis; n/a; neuropeptide Y; pancreatic islet; papillary muscle assay; photoaging; pleiotropy of CR genes; senescence-associated secretory phenotype; senoinflammation; SERCA2a; sirtuin; skin aging; skin appendages
• Persona (resp. second.): ChungHae-Young
• Sommario/riassunto: Recent biochemical studies indicate that calorie restriction (CR) is a widely accepted method for anti-aging intervention. CR and intermittent fasting (IF), which involves reduced calories but proper nutritional intake during specific periods, are interventions that can consistently promote health benefits, delay biological aging, and extend both average and maximal lifespan. Furthermore, CR can modulate age-related diseases such as Alzheimer's disease, atherosclerosis, diabetes, obesity, cancer, and others. Advances in omics technologies have provided a technical breakthrough that enabled the investigation of DNA, RNA, proteins, and other cellular molecules and their comprehensive interactions in a biological context. Nowadays, it is possible to analyze and integrate biological processes that occur in aging systems at the molecular level using state-of-the-art techniques such as next-generation sequencing (NGS), proteomics, lipidomics, metabolomics, and epigenomics. Omics technology and systems gerontology provide predictive information on CR effects, molecular mechanisms, and pathways underlying the anti-aging actions of CR and IF. This Special Issue, "The effects of calorie restriction and intermittent fasting on health and disease", focuses on the effects of calorie restriction and intermittent fasting on age-related inflammation, autophagy, metabolism, longevity, mitochondrial function, and age-related diseases.
• Titolo autorizzato: The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910557124303321
• Lo trovi qui: Univ. Federico II