Modulators of Oxidative Stress : Chemical and Pharmacological Aspects

• Autore: Saso Luciano
• Pubblicazione: Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020
• Descrizione fisica: 1 online resource (298 p.)
• Soggetto topico: Biology, life sciences; Research & information: general
• Soggetto non controllato: ADHD; antioxidant; antioxidants; ascorbic acid; biomarkers; C2C12 cells; cancer; cancer metabolism; cancer therapy; cardiac fibroblasts; chemoresistance; cytokines; deferoxamine; diabetes; dipeptidyl peptidase-4 inhibitors; epigenetics; ER stress; Ezetimibe; folic acid; gene expression; glucose; glycogen; glycolysis; high fat diet; hydroperoxide; immunomodulation; inflammation; insulin resistance; ionizing radiation; ischemia-reperfusion; ischemia/reperfusion; liver; mass spectrometry; metabolic stress; metabolomics; mice; miR7/MAFG/Nrf2 axe; mitochondria; MitoVitE; mRNA; N-acetylcysteine; n/a; NADPH; Nrf2; NRF2-KEAP1; nuclear factor kappa-light-chain-enhancer of activated B cells (NF-кB); olive tree; one-carbon metabolism; oxidative stress; pentose phosphate pathway; photobiomodulation; radioresistance; reactive oxygen species; reactive oxygen species (ROS); redox balance; ROS; secoirioids; sepsis; sex differences; sirtuin 3; stress resistance; type 2 diabetes; vitamin C; wound healing
• Persona (resp. second.): Gurer-OrhanHande; StepanićVišnja; SasoLuciano
• Sommario/riassunto: The book starts with the editors' preface summarizing the contributions of each of the following thirteen articles dealing with chemical and pharmacological aspects of the molecular modulators of the oxidative stress in regard to various therapeutic approaches in cardiovascular and neurodegenerative diseases, cancer, and diabetes. The seven articles present data from original research studies enlightening the roles and mechanisms of action of small molecular weight compounds (natural and synthetic; ascorbic acid/vitamin C, deferoxamine, N-acetylcysteine, MitoVitE, α-tocopherol, trolox, and ezetimibe) or proteins (SIRT3) in modulation of oxidative stress. In the six review papers, the authors present and discuss the possible therapeutic potential of novel approaches and compounds that are promising and deserve further investigation, in modulation of oxidative stress.
• Altri titoli varianti: Modulators of Oxidative Stress
• Titolo autorizzato: Modulators of Oxidative Stress
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910557769603321
• Lo trovi qui: Univ. Federico II