LEADER 04223nam 2201189z- 450 001 9910557769603321 005 20210501 035 $a(CKB)5400000000045665 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69251 035 $a(oapen)doab69251 035 $a(EXLCZ)995400000000045665 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aModulators of Oxidative Stress$eChemical and Pharmacological Aspects 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (298 p.) 311 08$a3-03943-228-1 311 08$a3-03943-229-X 330 $aThe book starts with the editors' preface summarizing the contributions of each of the following thirteen articles dealing with chemical and pharmacological aspects of the molecular modulators of the oxidative stress in regard to various therapeutic approaches in cardiovascular and neurodegenerative diseases, cancer, and diabetes. The seven articles present data from original research studies enlightening the roles and mechanisms of action of small molecular weight compounds (natural and synthetic; ascorbic acid/vitamin C, deferoxamine, N-acetylcysteine, MitoVitE, ?-tocopherol, trolox, and ezetimibe) or proteins (SIRT3) in modulation of oxidative stress. In the six review papers, the authors present and discuss the possible therapeutic potential of novel approaches and compounds that are promising and deserve further investigation, in modulation of oxidative stress. 517 $aModulators of Oxidative Stress 606 $aBiology, life sciences$2bicssc 606 $aResearch & information: general$2bicssc 610 $aADHD 610 $aantioxidant 610 $aantioxidants 610 $aascorbic acid 610 $abiomarkers 610 $aC2C12 cells 610 $acancer 610 $acancer metabolism 610 $acancer therapy 610 $acardiac fibroblasts 610 $achemoresistance 610 $acytokines 610 $adeferoxamine 610 $adiabetes 610 $adipeptidyl peptidase-4 inhibitors 610 $aepigenetics 610 $aER stress 610 $aEzetimibe 610 $afolic acid 610 $agene expression 610 $aglucose 610 $aglycogen 610 $aglycolysis 610 $ahigh fat diet 610 $ahydroperoxide 610 $aimmunomodulation 610 $ainflammation 610 $ainsulin resistance 610 $aionizing radiation 610 $aischemia-reperfusion 610 $aischemia/reperfusion 610 $aliver 610 $amass spectrometry 610 $ametabolic stress 610 $ametabolomics 610 $amice 610 $amiR7/MAFG/Nrf2 axe 610 $amitochondria 610 $aMitoVitE 610 $amRNA 610 $aN-acetylcysteine 610 $an/a 610 $aNADPH 610 $aNrf2 610 $aNRF2-KEAP1 610 $anuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) 610 $aolive tree 610 $aone-carbon metabolism 610 $aoxidative stress 610 $apentose phosphate pathway 610 $aphotobiomodulation 610 $aradioresistance 610 $areactive oxygen species 610 $areactive oxygen species (ROS) 610 $aredox balance 610 $aROS 610 $asecoirioids 610 $asepsis 610 $asex differences 610 $asirtuin 3 610 $astress resistance 610 $atype 2 diabetes 610 $avitamin C 610 $awound healing 615 7$aBiology, life sciences 615 7$aResearch & information: general 700 $aSaso$b Luciano$4edt$01280283 702 $aGurer-Orhan$b Hande$4edt 702 $aStepanic?$b Vis?nja$4edt 702 $aSaso$b Luciano$4oth 702 $aGurer-Orhan$b Hande$4oth 702 $aStepanic?$b Vis?nja$4oth 906 $aBOOK 912 $a9910557769603321 996 $aModulators of Oxidative Stress$93029082 997 $aUNINA