04188nam 2201165z- 450 991055776960332120231214132952.0(CKB)5400000000045665(oapen)https://directory.doabooks.org/handle/20.500.12854/69251(EXLCZ)99540000000004566520202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierModulators of Oxidative StressChemical and Pharmacological AspectsBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 electronic resource (298 p.)3-03943-228-1 3-03943-229-X The book starts with the editors’ preface summarizing the contributions of each of the following thirteen articles dealing with chemical and pharmacological aspects of the molecular modulators of the oxidative stress in regard to various therapeutic approaches in cardiovascular and neurodegenerative diseases, cancer, and diabetes. The seven articles present data from original research studies enlightening the roles and mechanisms of action of small molecular weight compounds (natural and synthetic; ascorbic acid/vitamin C, deferoxamine, N-acetylcysteine, MitoVitE, α-tocopherol, trolox, and ezetimibe) or proteins (SIRT3) in modulation of oxidative stress. In the six review papers, the authors present and discuss the possible therapeutic potential of novel approaches and compounds that are promising and deserve further investigation, in modulation of oxidative stress.Modulators of Oxidative Stress Research & information: generalbicsscBiology, life sciencesbicsscascorbic aciddeferoxamineN-acetylcysteineischemia/reperfusioncardiac fibroblastsreactive oxygen speciesphotobiomodulationreactive oxygen species (ROS)nuclear factor kappa-light-chain-enhancer of activated B cells (NF-кB)cancerdiabeteswound healingglucosepentose phosphate pathwayNADPHredox balanceglycogenglycolysisstress resistanceinsulin resistanceimmunomodulationinflammationolive treeoxidative stresssecoirioidssirtuin 3high fat dietsex differencesmicemetabolic stressantioxidantsADHDNrf2NRF2-KEAP1ROScancer metabolismantioxidantcancer therapychemoresistanceradioresistancesepsisMitoVitEmitochondriagene expressioncytokinesmRNAvitamin Cfolic acidone-carbon metabolismC2C12 cellsmetabolomicsmass spectrometrytype 2 diabetesdipeptidyl peptidase-4 inhibitorsbiomarkersER stressEzetimibeischemia-reperfusionionizing radiationliverhydroperoxideepigeneticsmiR7/MAFG/Nrf2 axeResearch & information: generalBiology, life sciencesSaso Lucianoedt1280283Gurer-Orhan HandeedtStepanić VišnjaedtSaso LucianoothGurer-Orhan HandeothStepanić VišnjaothBOOK9910557769603321Modulators of Oxidative Stress3029082UNINA