04223nam 2201189z- 450 991055776960332120210501(CKB)5400000000045665(oapen)https://directory.doabooks.org/handle/20.500.12854/69251(oapen)doab69251(EXLCZ)99540000000004566520202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierModulators of Oxidative StressChemical and Pharmacological AspectsBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (298 p.)3-03943-228-1 3-03943-229-X The book starts with the editors' preface summarizing the contributions of each of the following thirteen articles dealing with chemical and pharmacological aspects of the molecular modulators of the oxidative stress in regard to various therapeutic approaches in cardiovascular and neurodegenerative diseases, cancer, and diabetes. The seven articles present data from original research studies enlightening the roles and mechanisms of action of small molecular weight compounds (natural and synthetic; ascorbic acid/vitamin C, deferoxamine, N-acetylcysteine, MitoVitE, α-tocopherol, trolox, and ezetimibe) or proteins (SIRT3) in modulation of oxidative stress. In the six review papers, the authors present and discuss the possible therapeutic potential of novel approaches and compounds that are promising and deserve further investigation, in modulation of oxidative stress.Modulators of Oxidative Stress Biology, life sciencesbicsscResearch & information: generalbicsscADHDantioxidantantioxidantsascorbic acidbiomarkersC2C12 cellscancercancer metabolismcancer therapycardiac fibroblastschemoresistancecytokinesdeferoxaminediabetesdipeptidyl peptidase-4 inhibitorsepigeneticsER stressEzetimibefolic acidgene expressionglucoseglycogenglycolysishigh fat diethydroperoxideimmunomodulationinflammationinsulin resistanceionizing radiationischemia-reperfusionischemia/reperfusionlivermass spectrometrymetabolic stressmetabolomicsmicemiR7/MAFG/Nrf2 axemitochondriaMitoVitEmRNAN-acetylcysteinen/aNADPHNrf2NRF2-KEAP1nuclear factor kappa-light-chain-enhancer of activated B cells (NF-кB)olive treeone-carbon metabolismoxidative stresspentose phosphate pathwayphotobiomodulationradioresistancereactive oxygen speciesreactive oxygen species (ROS)redox balanceROSsecoirioidssepsissex differencessirtuin 3stress resistancetype 2 diabetesvitamin Cwound healingBiology, life sciencesResearch & information: generalSaso Lucianoedt1280283Gurer-Orhan HandeedtStepanić VišnjaedtSaso LucianoothGurer-Orhan HandeothStepanić VišnjaothBOOK9910557769603321Modulators of Oxidative Stress3029082UNINA