Recent Progress in Solid Dispersion Technology
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| Autore: |
Kawakami Kohsaku
|
| Titolo: |
Recent Progress in Solid Dispersion Technology
|
| Pubblicazione: | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica: | 1 electronic resource (204 p.) |
| Soggetto non controllato: | thermodynamic modeling |
| molecular dynamics simulation | |
| poorly soluble drugs | |
| amorphous solid dispersions | |
| dissolution enhancement | |
| crystallization tendency | |
| continuous processing | |
| stability | |
| milling | |
| granulation | |
| thermal analysis | |
| amorphous | |
| ball milling | |
| pharmaceutical glass | |
| dissolution | |
| rebamipide | |
| poloxamer | |
| classification | |
| polyelectrolytes | |
| amorphisation | |
| self-assembly | |
| dissolution rate | |
| miscibility | |
| bioavailability | |
| solubility | |
| evaporation | |
| mesoporous | |
| polyelectrolyte excipient matrix | |
| polymer | |
| bicaludamide | |
| phase diagram | |
| Weibull dissolution model | |
| spectroscopic techniques | |
| anticancer drugs | |
| manufacturing methods | |
| nucleation | |
| molecular complex | |
| nanoaggregates | |
| enrofloxacin | |
| accelerated stability test | |
| solubility enhancement | |
| amorphous solid dispersion | |
| tadalafil | |
| process development | |
| amorphous polymeric salt | |
| Wood’s apparatus | |
| hot melt extrusion | |
| solid dispersions | |
| intrinsic dissolution rate | |
| solid dispersion | |
| interaction | |
| crystallization | |
| spray drying | |
| characterization | |
| ciprofloxacin | |
| Sommario/riassunto: | Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics. |
| Titolo autorizzato: | Recent Progress in Solid Dispersion Technology |
| ISBN: | 3-03921-502-7 |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910367756203321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |