LEADER 03503nam 2200949z- 450 001 9910367756203321 005 20231214133032.0 010 $a3-03921-502-7 035 $a(CKB)4100000010106155 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/57786 035 $a(EXLCZ)994100000010106155 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aRecent Progress in Solid Dispersion Technology 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 215 $a1 electronic resource (204 p.) 311 $a3-03921-501-9 330 $aAmorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD?s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics. 610 $athermodynamic modeling 610 $amolecular dynamics simulation 610 $apoorly soluble drugs 610 $aamorphous solid dispersions 610 $adissolution enhancement 610 $acrystallization tendency 610 $acontinuous processing 610 $astability 610 $amilling 610 $agranulation 610 $athermal analysis 610 $aamorphous 610 $aball milling 610 $apharmaceutical glass 610 $adissolution 610 $arebamipide 610 $apoloxamer 610 $aclassification 610 $apolyelectrolytes 610 $aamorphisation 610 $aself-assembly 610 $adissolution rate 610 $amiscibility 610 $abioavailability 610 $asolubility 610 $aevaporation 610 $amesoporous 610 $apolyelectrolyte excipient matrix 610 $apolymer 610 $abicaludamide 610 $aphase diagram 610 $aWeibull dissolution model 610 $aspectroscopic techniques 610 $aanticancer drugs 610 $amanufacturing methods 610 $anucleation 610 $amolecular complex 610 $ananoaggregates 610 $aenrofloxacin 610 $aaccelerated stability test 610 $asolubility enhancement 610 $aamorphous solid dispersion 610 $atadalafil 610 $aprocess development 610 $aamorphous polymeric salt 610 $aWood?s apparatus 610 $ahot melt extrusion 610 $asolid dispersions 610 $aintrinsic dissolution rate 610 $asolid dispersion 610 $ainteraction 610 $acrystallization 610 $aspray drying 610 $acharacterization 610 $aciprofloxacin 700 $aKawakami$b Kohsaku$4auth$01328855 906 $aBOOK 912 $a9910367756203321 996 $aRecent Progress in Solid Dispersion Technology$93039034 997 $aUNINA