Recent Advances in Antibody Therapeutics

• Autore: Heo Yong-Seok
• Pubblicazione: Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
• Descrizione fisica: 1 online resource (238 p.)
• Soggetto topico: Chemistry; Research & information: general
• Soggetto non controllato: affinity maturation; agonist antibody; anti-angiogenesis; anti-cancer antibody; antibodies; antibody; antibody engineering; antibody therapeutics; antibody therapy; antibody-drug conjugates; antigen; asthma; atherosclerosis; binding assays; bioassays; biochemical and physicochemical properties; biomarker; biophysical properties; bispecific antibodies; bladder cancer; blood-brain barrier; brain shuttle; C2_2E12; cell fate; combinatorial antibody library; computational methods; cost-effectiveness; cytomegalovirus; delta-like ligand; disposition; enfortumab vedotin; erdafitinib; Fc binding; G protein-coupled receptor; HPV cancer therapy; HPV oncoproteins; HPV-associated cancer; Human papillomaviruses; immune checkpoint inhibitors; inflammation; interleukin 33; intracellular antibodies; irinotecan; mechanisms of action; membrane protein; molecular Trojan horse; monoclonal antibody; n/a; nanobody; paclitaxel; peptide/major histocompatibility complex class I complex; phage display; pharmacokinetics; potency assays; receptor-binding domain; receptor-mediated transcytosis; recombinant antibodies; refractory asthma; research cell bank; sacituzumab govitecan; SARS-CoV-2; scFv; single-chain antibody fragment; spike protein; ST2 receptor; T-cell-receptor-like antibody; therapeutic antibody; transferrin; VEGF; yeast surface display
• Persona (resp. second.): HeoYong-Seok
• Sommario/riassunto: Since first receiving approval in 1986, antibody-based therapeutics have been the most successful modality for the treatment of various diseases. This Special Issue of IJMS, "Recent Advances in Antibody Therapeutics", presents leading-edge articles and reviews for discovery, development, and clinical applications of therapeutic antibodies, covering antibody drug conjugates (ADCs), GPCR-targeting antibodies, a functional antibody screening, bioassay of bispecific antibodies, antibody applications for cardiovascular diseases, antibody delivery to CNS, etc. The excellent studies in this Special Issue would valuable insight for scientists and clinicians in the field of therapeutic antibodies
• Titolo autorizzato: Recent Advances in Antibody Therapeutics
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910580204803321
• Lo trovi qui: Univ. Federico II