04164nam 2201177z- 450 991058020480332120231214133255.0(CKB)5690000000012042(oapen)https://directory.doabooks.org/handle/20.500.12854/87408(EXLCZ)99569000000001204220202207d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierRecent Advances in Antibody TherapeuticsBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (238 p.)3-0365-4353-8 3-0365-4354-6 Since first receiving approval in 1986, antibody-based therapeutics have been the most successful modality for the treatment of various diseases. This Special Issue of IJMS, “Recent Advances in Antibody Therapeutics”, presents leading-edge articles and reviews for discovery, development, and clinical applications of therapeutic antibodies, covering antibody drug conjugates (ADCs), GPCR-targeting antibodies, a functional antibody screening, bioassay of bispecific antibodies, antibody applications for cardiovascular diseases, antibody delivery to CNS, etc. The excellent studies in this Special Issue would valuable insight for scientists and clinicians in the field of therapeutic antibodiesResearch & information: generalbicsscChemistrybicsscinterleukin 33ST2 receptorscFvC2_2E12bladder cancerantibodiesimmune checkpoint inhibitorsantibody-drug conjugatessacituzumab govitecanenfortumab vedotinerdafitinibcost-effectivenessG protein-coupled receptormembrane proteinantigentherapeutic antibodyanti-angiogenesisdelta-like ligandirinotecanpaclitaxelVEGFSARS-CoV-2spike proteinreceptor-binding domainphage displaymonoclonal antibodycytomegaloviruspeptide/major histocompatibility complex class I complexT-cell-receptor-like antibodyaffinity maturationyeast surface displaycombinatorial antibody libraryagonist antibodycell fatebispecific antibodiesbioassaysmechanisms of actionbinding assayspotency assaysatherosclerosisinflammationantibody therapyblood-brain barrierantibodypharmacokineticsdispositionbiochemical and physicochemical propertiesFc bindingreceptor-mediated transcytosisbrain shuttlemolecular Trojan horsetransferrinanti-cancer antibodyantibody engineeringbiophysical propertiescomputational methodsresearch cell bankantibody therapeuticsrecombinant antibodiesintracellular antibodiessingle-chain antibody fragmentnanobodyHuman papillomavirusesHPV oncoproteinsHPV-associated cancerHPV cancer therapyasthmarefractory asthmabiomarkerResearch & information: generalChemistryHeo Yong-Seokedt1332302Heo Yong-SeokothBOOK9910580204803321Recent Advances in Antibody Therapeutics3040802UNINA