04197nam 2201201z- 450 991058020480332120220706(CKB)5690000000012042(oapen)https://directory.doabooks.org/handle/20.500.12854/87408(oapen)doab87408(EXLCZ)99569000000001204220202207d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierRecent Advances in Antibody TherapeuticsBaselMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (238 p.)3-0365-4353-8 3-0365-4354-6 Since first receiving approval in 1986, antibody-based therapeutics have been the most successful modality for the treatment of various diseases. This Special Issue of IJMS, "Recent Advances in Antibody Therapeutics", presents leading-edge articles and reviews for discovery, development, and clinical applications of therapeutic antibodies, covering antibody drug conjugates (ADCs), GPCR-targeting antibodies, a functional antibody screening, bioassay of bispecific antibodies, antibody applications for cardiovascular diseases, antibody delivery to CNS, etc. The excellent studies in this Special Issue would valuable insight for scientists and clinicians in the field of therapeutic antibodiesChemistrybicsscResearch & information: generalbicsscaffinity maturationagonist antibodyanti-angiogenesisanti-cancer antibodyantibodiesantibodyantibody engineeringantibody therapeuticsantibody therapyantibody-drug conjugatesantigenasthmaatherosclerosisbinding assaysbioassaysbiochemical and physicochemical propertiesbiomarkerbiophysical propertiesbispecific antibodiesbladder cancerblood-brain barrierbrain shuttleC2_2E12cell fatecombinatorial antibody librarycomputational methodscost-effectivenesscytomegalovirusdelta-like liganddispositionenfortumab vedotinerdafitinibFc bindingG protein-coupled receptorHPV cancer therapyHPV oncoproteinsHPV-associated cancerHuman papillomavirusesimmune checkpoint inhibitorsinflammationinterleukin 33intracellular antibodiesirinotecanmechanisms of actionmembrane proteinmolecular Trojan horsemonoclonal antibodyn/ananobodypaclitaxelpeptide/major histocompatibility complex class I complexphage displaypharmacokineticspotency assaysreceptor-binding domainreceptor-mediated transcytosisrecombinant antibodiesrefractory asthmaresearch cell banksacituzumab govitecanSARS-CoV-2scFvsingle-chain antibody fragmentspike proteinST2 receptorT-cell-receptor-like antibodytherapeutic antibodytransferrinVEGFyeast surface displayChemistryResearch & information: generalHeo Yong-Seokedt1332302Heo Yong-SeokothBOOK9910580204803321Recent Advances in Antibody Therapeutics3040802UNINA