Plasma in Cancer Treatment

• Autore: Bogaerts Annemie
• Pubblicazione: Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
• Descrizione fisica: 1 online resource (358 p.)
• Soggetto topico: Medicine and Nursing
• Soggetto non controllato: anticancer drugs; apoptosis; bone cancer; breast cancer; cancer; cancer selectivity; cell adhesion; cell communication; cellular uptake; cervical cancer treatment; cervical intraepithelial neoplasia; cervical intraepithelial neoplasia (CIN); cholangiocarcinoma; cold atmospheric plasma; cold atmospheric plasma (CAP); cold atmospheric pressure plasma; cold physical plasma; cold plasma; combination therapy; communication junctions; cytotoxicity; dendritic cells; dielectric barrier discharge; DNA-damage; electric pulses; electroporation; extracellular matrix (ECM); extracellular vesicles; free radicals; genome-wide expression; gold quantum dots; high frequency electrosurgery; human glioblastoma; immunogenic cell death; indirect treatment; innovative therapy; invasiveness; kINPen; long-lived reactive oxygen and nitrogen species; long-lived reactive species; macrophages; melanoma; multicellular tumor spheroids; n/a; nanomaterials; non-invasive plasma treatment (NIPP); non-thermal atmospheric pressure plasma (NTP); non-thermal plasma; nonthermal biocompatible plasma; olaparib; oncology; organotypic model; osteosarcoma; ovarian cancer; p38/MAPK pathway; pancreatic cancer; pancreatic stellate cells; PARP-inhibitor; plasma; plasma jet; Plasma lipid interactions; plasma medicine; plasma selectivity; plasma treatment; plasma-activated liquid; plasma-activated liquids; plasma-activated Ringer's lactate solution; plasma-treated liquid; plasma-treated phosphate-buffered saline; pulsed electric field amplitude; radiation therapy; radio-frequency discharge; Raman imaging; Raman microspectroscopy; reactive oxygen and nitrogen species; reactive oxygen and nitrogen species (ROS); reactive oxygen species; reactive species; Ringer's saline; ROS; screening; selectivity; soft jet plasma; three-dimensional in vitro culture models; tissue penetration; tumor cells; tumor spheroids; tumour microenvironment (TME)
• Persona (resp. second.): Privat-MaldonadoAngela; BogaertsAnnemie
• Sommario/riassunto: In the last decade, research on cold atmospheric plasma (CAP) has significantly advanced our understanding of the effect of CAP on cancer cells and their potential for cancer treatment. This effect is due to the reactive oxygen and nitrogen species (RONS) created by plasma. This has been demonstrated for different cancer cell lines and the first clinical trials showed promising results. In addition, plasma could be combined with other treatments-such as immunotherapy-to boost its anticancer activity. The addition of new research tools to study the response of cancer cells to CAP-such as 3D in vitro, in ovo, and in vivo models and in silico approaches-as well as the use of -OMICS technologies could aid in unravelling the underlying mechanisms of CAP in cancer treatment. In order to progress towards widespread clinical application of CAP, an integrated study of the multidimensional effect of CAP in cancer treatment is essential. In this book, reviews and original research papers are published that provide new insights into the mechanisms of cold atmospheric plasma in cancer treatment, based on in vitro and in vivo experiments, clinical studies, as well as computer modeling.
• Titolo autorizzato: Plasma in Cancer Treatment
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910557527603321
• Lo trovi qui: Univ. Federico II