Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot

• Autore: Jongbloed Monique
• Pubblicazione: Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
• Descrizione fisica: 1 online resource (372 p.)
• Soggetto topico: Public health and preventive medicine
• Soggetto non controllato: acute aortic syndrome; anomalous left subclavian artery; aorta; aortic regurgitation; aortic stenosis; aortic surgery; aortic valve replacement; aortic wall; arrhythmogenic right ventricular dysplasia; arteria lusoria; arterial duct; arterial switch operation; asymptomatic; atrioventricular valve; Bentall; bicuspid aortic valve; candidate genes; cardiac development; cardiac fields; cardiac progenitor cells; cardiomyocyte; cardiovascular development; cardiovascular disease; cardiovascular pathogenesis; cartilage; cell identity; cell polarity; cleft palate; compact myocardium; congenital heart defects; congenital heart disease; coronary arteries; coronary artery; coronary artery anatomy; coronary complications; cushion; developmental biology; discordant phenotype; dissection of ductus arteriosus; DNA methylation; ductus arteriosus; early surgery; endocardial cushions; endocardial fibro-elastosis; endocardium; epicardium; epigenetics; esophageal compression; fetal aortic stenosis; foramen of Panizza; free edge folding; genetics; heart tube; homograft; imaging; Kommerell's diverticulum; lateral cushion; left aorta; Leiden Convention coronary coding system; lineage tracing; Lipton classification; loeys dietz syndrome-5; major cushion; monozygotic twins; myofibroblasts; myxomatous degeneration; neointima; neural crest; neural crest cell; original leaflet; outflow tract; outflow tract septation; pharyngeal arch arteries; pharyngeal arch artery; pharyngeal ectoderm; postmortem histology; prenatal ultrasound; progenitor specification; proliferation; pulmonary trunk; Rac1; remodeling; rienhoff syndrome; right aorta; right sided aortic arch; second heart field; semilunar valves; signaling networks; single coronary artery; speckle tracking analysis; sudden unexpected intrauterine death; superimposed tissue; surgical; Tetralogy of Fallot; trabeculation; tracheal compression; transcription factor AP-2α; transcriptome; transforming growth factor beta-3; transposition great arteries coronary anatomy; transposition of the great arteries; tunica media; valve; variations; watchful waiting
• Persona (resp. second.): PoelmannRobert; JongbloedMonique
• Sommario/riassunto: The arterial pole is one of the most complex parts of the heart both in development and disease. It involves the collaboration and orchestration of contributions from the first and second heart fields as well as the neural crest. The precursor cells differentiate into endocardial cushions and putative cardiac valves, the myocardium, and epicardium of the heart, but also into the different layers of the main arterial vessels. These include not only the aorta and the pulmonary trunk but also the pulmonary and coronary arteries, and during development, the arterial duct. Many transcriptional and signaling networks act in timely concert to acquire the proper asymmetric development and function and pressure and flow dynamics. This is not only a human or even mammalian 'enterprise,' but is also taking place in so-called ancestral forms from fish to reptiles, including birds. In humans, it is small wonder that many clinical syndromes may arise when something in this complexity is amiss. This Special Issue of JCDD contains contributions focussed on the heart fields, congenital cardiac malformations and associated syndromes, with special emphasis on the cardiac outflow tract. The Issue is devoted to Prof. Dr. Adriana Gittenberger-de Groot, who dedicated her extensive career to research on cardiovascular development.
• Altri titoli varianti: Leaders in Cardiovascular Research
• Titolo autorizzato: Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910585946203321
• Lo trovi qui: Univ. Federico II