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In-Cell NMR Spectroscopy: Biomolecular Structure and Function



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Autore: Burz David S Visualizza persona
Titolo: In-Cell NMR Spectroscopy: Biomolecular Structure and Function Visualizza cluster
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute, 2020
Descrizione fisica: 1 online resource (152 p.)
Soggetto topico: Biology, life sciences
Soggetto non controllato: 2D INADEQUATE
Adenylate kinase
antimicrobial peptide
cross-correlated relaxation
crystalline and amorphous starch
Dihydrofolate reductase
DNA
DNP
drug discovery
enzyme activity
enzyme kinetics
in-cell NMR
in-situ NMR
intrinsically disordered proteins
lipid membrane
live cell
magic-angle spinning
mammalian cells
MARK2 phosphorylation
mRNA
NMR spectroscopy
non-uniform sampling 2
paramagnetic effects
post-translational modifications
protein dynamics
protein interactions
protein modification
protein NMR
protein structure
protein structure determination 1
protein structure-function
review
Ribosome
rRNA
solid-state NMR
spectrum reconstruction 3
structural calculation 4
structure function
target engagement
Tau
Thioredoxin
Thymidylate synthase
time-resolved NMR
whole cell NMR
Persona (resp. second.): ShekhtmanAlexander
Sommario/riassunto: This Special Issue examines state-of-the-art in-cell NMR spectroscopy as it relates to biological systems of increasing complexity. The compendia of research and recent innovations from prominent laboratories in the field of solid state and solution in-cell NMR spectroscopy, metabolomics and technology development are presented. The work establishes in-cell NMR spectroscopy as the premier method for determining the structures and interaction capabilities of biological molecules at high resolution within the delicately intricate interior of living cells, and the means of utilizing cells as living laboratories to directly assess the effects of exogenous and endogenous stimuli on cell physiology.]
Altri titoli varianti: In-Cell NMR Spectroscopy
Titolo autorizzato: In-Cell NMR Spectroscopy: Biomolecular Structure and Function  Visualizza cluster
ISBN: 3-03928-255-7
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910404084303321
Lo trovi qui: Univ. Federico II
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