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Marine Compounds and Cancer 2020



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Autore: Honecker Friedemann Visualizza persona
Titolo: Marine Compounds and Cancer 2020 Visualizza cluster
Pubblicazione: Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Descrizione fisica: 1 online resource (480 p.)
Soggetto topico: Medicine and Nursing
Soggetto non controllato: 12-deacetyl-12-epi-scalaradial
3-alkylpyridinium polymers
A375 and HeLa cell lines
A549 cells
ABC transporter
actinomycin
AD0157
adriamycin resistance
Aeroplysinin
Akt
angiogenesis
angiogenesis inhibitor
ansamycins
anthranilic acid
anti-angiogenesis
anti-angiogenic
anti-cancer
anti-metastatic activity
anti-proliferation
anti-proliferative
antiangiogenesis
antiangiogenic
antibacterial
Antibody Drug Conjugates (ADCs)
anticancer
anticancer activity
anticancer agent
anticancer immunity
anticarcinogenic
anticoagulant
anticoagulation
antifouling
Antimicrobial peptide (AMP)
antioxidant
antiproliferative
antiproliferative activity
antitumor
antitumor activities
antitumoral
antitumour
AP-1
apoptosis
apoptosis-inducing activity
approved antitumor agents
araguspongine C
arrest of cell cycle
Aspergillus
autophagy
autophagy inducers
autophagy inhibitors
azoxymethane
BCRP/ABCG2
BEL-7402 cell
benzo[a]pyrene
bioactive natural product
bioanalysis
bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM)
bonnethead shark
breast cancer
breast cancer cells
Brevianamide
brominated indoles
bromophenol
buccal gland
c-JUN
c-Met
C15 acetogenins
camptothecin
cancer
Cancer
cancer genes
cancer preventive
cancer progression
Cantabrian Sea-derived actinobacteria
carbocyclic analogue
carcinoembryonic antigen
Caribbean sponge
carotenoid
carotenoids
caspase cascade
cell adhesion
cell adhesion molecules
cell cycle
cell cycle arrest
cell migration
cembranoids
chemical conjugation
chemoprevention
chemopreventive
chemosensitization
chemotherapy
chimera
CHOP
chromatography
circulating tumor cells
cisplatin
clinical trials
colorectal cancer
cooperative binding
cyclin D1
cyclin-dependent kinase
CYP1A1
cystatin F
cystatin superfamily
cytokine release
cytoskeleton
cytotoxic activity
cytotoxicity
deep-sea
depolymerisation
dibromotyrosine
dieckol
divergolides
DNA minor groove binder
drug discovery
Ecklonia cava
elisidepsin
EMT
endoperoxide
endophytic fungus
endothelial cells
energy stress
epigonal organ
epithelial-mesenchymal transition
ER-stress
ET-743
evolution
FAK
fascaplysin
fatty acid 2-hydroxylase
fatty acids
FAU
FBDD
fucoidan
fucoxanthin
fumigaclavine C
gemcitabine
gene expression
glioblastoma
gliotoxin
glucocorticoid receptor
glycosaminoglycans
gorgonian
Haliclona gracilis
HeLa cells
heparan sulphate
heparanase
hepatocellular carcinoma
HER2
HIF-1
hippuristanol
HSP90
human lung cancer
human normal diploid fibroblast (TIG-1 cells)
human sarcoma cell line (HT1080 cells)
humulane sesquiterpenoids
hybridization
hydroxylated lipids
hypoxia
hypoxia-inducible factor-1
IL-6
in vivo model
inflammation
inhibitor
integrin β1
invasion
isatin
Isofistularin
itampolin A
jaspine B
JNK1/2
Jurkat
kalkitoxin
kunitz type inhibitor
Lampetra morii
Leathesia nana
Leptogorgia
leukemia
lipid rafts
low molecular weight fucoidan extract
low toxic
LS-1
lung cancer
lung metastasis
Lyngbya majuscula
macrolide
mangrove-derived actinomycete
manzamine A
MAPK/ERK pathway
marangucyclines
marine antitumor agents
marine biotechnology
marine compound
marine drug
marine drugs
marine fungus
marine metabolites
marine mollusc
marine natural products
marine organisms
marine sponges
marine-derived drugs
Marthasterias glacialis L.
MCP-1
mechanisms of action
melanoma
membrane permeabilization
metastasis
microalgae
Micromonospora
migration
mitochondria
mitochondria toxin
mitochondrial pathway
mitochondrial dysfunction
molecular docking
molecular mechanisms
molecular modeling
molecular oncology
Moorea producens
MRP1/ABCC1
multi-drug resistant leukemia
multidrug resistance
Mycalin A
Mycochromenic acid derivative
N-Ras
n/a
nanoparticle
naphthopyrones
natural marine compounds
natural product
natural products
neuroblastoma-rat sarcoma
NF-κB
NF-κB signaling
nicotine
nicotinic acetylcholine receptor
non-small cell lung cancer
non-small cell lung cancer (NSCLC)
non-small cell lung carcinoma
nonfunctioning pituitary adenomas
novel inhibitor
NSCLC
Nur77
osteosarcoma
oxidative stress
oxidative stress
P-gp/ABCB1
P2X7 receptor
p38
p38/ERK
p38α
p65
pachastrissamine
palmitic acid
paulomycins
pazopanib
PEL
Penicillium brevicompactum
Penicillium paneum
phase I
pheochromocytoma and paraganglioma
phlorotannins
phycocyanin
PI3K/Akt
plakortide
plitidepsin
pollution
poly(ADP-ribose)-polymerase inhibitor
polyoxygenated steroids
polyphenols
polysaccharides
Porifera
porifera/sponge
preclinical
programmed cell death
programmed cell death-ligand 1
programmed cell death-ligand 2
proliferation
prostate cancer
proteasomal degradation
proteomic
pseudopterosin
puupehenones
pyrrolidinedione
reactive oxygen species
RGD motif
ribosomal protein genes
ROS
RPS30
safety
Sarcophyton ehrenbergi
sea anemone
sea cucumbers
seaweed
secondary metabolites
sediment
selenium-containing polysaccharide-protein complex
Sepia ink polysaccharides
shrimp
signal transduction
sinulariolide
sipholenol A
small cell lung cancer
SNORA62
snoRNA
SNU-C5/5-FU
soft coral
soft tissue sarcoma
soft tissue sarcoma
sphingosine kinase inhibitor
sponge
sponges
STAT3
Streptomyces sp. SCSIO 11594
synergism
synthetic analogues
SZ-685C
targeted therapy
terpenes
tetracenomycin X
TGF-β signaling
Thalassia testudinum
thalassiolin B
therapeutic compounds
Tilapia piscidin 4 (TP4)
TNFα
Topo I inhibitor
topoisomerase
trabectedin
triterpene glycosides
TRPM7
tumor cell line
tumor microenvironment
tumor-associated macrophages
Ulva fasciata
uveal melanoma
VEGF
virtual screening
xyloketal B
α9-nicotinic acetylcholine receptors (nAChRs)
αO-conotoxin GeXIVA
β1-integrin
λ-carrageenan
Persona (resp. second.): DyshlovoySergey A
HoneckerFriedemann
Sommario/riassunto: The very first marine-derived anticancer drug, Cytarabine (aka Ara-C, Cytosar-U®), was approved by the FDA in 1969 for the treatment of leukemia. At the beginning of 2021, the list of approved marine-derived anticancer drugs consists of nine substances, five of which received approval within the last two years, demonstrating the rapid evolution of the field. The current book is a collection of scientific articles related to the exponentially growing field of anticancer marine compounds. These articles cover the whole field, from agents with cancer-preventive activity, to novel and previously characterized compounds with anticancer activity, both in vitro and in vivo, as well as the latest status of compounds under clinical development.
Titolo autorizzato: Marine Compounds and Cancer 2020  Visualizza cluster
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910557339303321
Lo trovi qui: Univ. Federico II
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